Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

336 questions · 354 findings · 32 reviews · Haematology

No studies found 71 · 20.1%GRADE not reported 33 · 9.3%Very low 70 · 19.8%Low 82 · 23.2%Moderate 75 · 21.2%High 23 · 6.5%

Prophylactic platelet transfusion vs non prophylactic or therapeutic platelet transfusion

Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder

Prophylactic platelet transfusion showed no clear difference in bleeding: Numbers of patients with at least one significant bleeding… compared with non prophylactic or therapeutic platelet transfusion (low certainty).

1 finding from 1 review

Prophylactic platelet transfusion with one dose schedule vs prophylactic platelet transfusions with another dose schedule

Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder

Prophylactic platelet transfusion with one dose schedule showed no clear difference in bleeding Number of participants with a significant bleeding event ‐… compared with prophylactic platelet transfusions with another dose schedule (high certainty).

2 findings from 1 review

Prophylactic platelet transfusion with one dose schedule vs prophylactic platelet transfusions with another dose schedule

Bleeding Number of days with significant bleeding ‐ Low dosage platelet transfusions versus standard dosage platelet transfusions · People with a haematological disorder
1 finding from 1 review

Prophylactic platelet transfusion with one dose schedule vs prophylactic platelet transfusions with another dose schedule

Bleeding: Number of days with significant bleeding ‐ High dosage platelet transfusions versus standard dosage platelet transfusions · People with a haematological disorder
1 finding from 1 review

Prophylactic platelet transfusion with one dose schedule vs prophylactic platelet transfusions with another dose schedule

Mortality: secondary to bleeding · People with a haematological disorder
2 findings from 1 review

Prophylactic platelet transfusion vs platelet‐poor plasma

Bleeding: Numbers of patients with at least one significant bleeding event · People with a haematological disorder

It is very uncertain whether prophylactic platelet transfusion changes number of participants with a significant bleeding event compared with platelet‐poor plasma (very low certainty).

1 finding from 1 review

Prophylactic platelet transfusion vs platelet‐poor plasma

Mortality: secondary to bleeding · People with a haematological disorder

It is very uncertain whether prophylactic platelet transfusion changes mortality: secondary to bleeding compared with platelet‐poor plasma (very low certainty).

1 finding from 1 review