Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,747 questions · 3,943 findings · 594 reviews

No studies found 784 · 19.9%GRADE not reported 530 · 13.4%Very low 1,040 · 26.4%Low 981 · 24.9%Moderate 444 · 11.3%High 164 · 4.2%

Intervention not reported

Cohort study MMR ‐ children with at least 1 sibling with type 1 diabetes · children 9 months to 15 years old

The intervention showed no clear difference in cohort study MMR ‐ children with at least 1 sibling with type 1… (low certainty).

1 finding from 1 review

Intervention not reported

Cohort study (rate ratio) ‐ all ages · children 9 months to 15 years old

The intervention showed no clear difference in cohort study (rate ratio) ‐ all ages (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies (risk ratio) ‐ all ages · children 9 months to 15 years old

The intervention showed no clear difference in cohort studies (risk ratio) ‐ all ages (low certainty).

1 finding from 1 review

Intervention not reported

Cohort study (rate ratio) · children 9 months to 15 years old

It is very uncertain whether the intervention changes cohort study (rate ratio) (very low certainty).

1 finding from 1 review

Intervention not reported

Cohort study (risk ratio) · children 9 months to 15 years old

The intervention showed no clear difference in cohort study (risk ratio) (low certainty).

1 finding from 1 review

Intervention not reported

Cohort study ‐ rhinoconjunctivitis · children 9 months to 15 years old

The intervention showed no clear difference in cohort study ‐ rhinoconjunctivitis (low certainty).

1 finding from 1 review

Intervention not reported

Cohort study ‐ hypersensitivity/allergy · children 9 months to 15 years old

The intervention showed no clear difference in cohort study ‐ hypersensitivity/allergy (low certainty).

1 finding from 1 review

Intervention not reported

Case control ‐ hay fever · children 9 months to 15 years old

The intervention showed no clear difference in case control ‐ hay fever (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ Jeryl Lynn strain ‐ unspecified number of doses · children 9 months to 15 years old

The intervention may leads to lower cohort studies ‐ Jeryl Lynn strain ‐ unspecified number of doses (low certainty).

1 finding from 1 review

Intervention not reported

Case‐control ‐ acute leukaemia · children 9 months to 15 years old

The intervention showed no clear difference in case‐control ‐ acute leukaemia (low certainty).

1 finding from 1 review

Intervention not reported

Case‐control ‐ acute lymphoblastic leukaemia · children 9 months to 15 years old

The intervention showed no clear difference in case‐control ‐ acute lymphoblastic leukaemia (low certainty).

1 finding from 1 review

Intervention not reported

Case‐control ‐ acute myeloblastic leukaemia · children 9 months to 15 years old

The intervention showed no clear difference in case‐control ‐ acute myeloblastic leukaemia (low certainty).

1 finding from 1 review

Intervention not reported

Case‐control ‐ multiple sclerosis · children 9 months to 15 years old

The intervention showed no clear difference in case‐control ‐ multiple sclerosis (low certainty).

1 finding from 1 review

Intervention not reported

Case‐control ‐ ADEM · children 9 months to 15 years old

The intervention showed no clear difference in case‐control ‐ ADEM (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series (hospitalisations) ‐ hospitalisations ‐ risk period: 0 to 60 days · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series (hospitalisations) ‐ hospitalisations ‐… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 0 to 5 days · children 9 months to 15 years old

The intervention may leads to higher self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 0… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 6 to 60 days · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 6… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ lobar pneumonia ‐ lobar pneumonia risk period (0 to 90 days) · children 9 months to 15 years old

The intervention may leads to lower self‐controlled case series ‐ lobar pneumonia ‐ lobar pneumonia risk… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ invasive bacterial infections ‐ invasive bacterial infections risk period (0 to 90 days) · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series ‐ invasive bacterial infections ‐… (low certainty).

1 finding from 1 review