Cleft lip (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft lip (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Cleft palate (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in cleft palate (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Congenital cardiovascular anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in congenital cardiovascular anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Other congenital anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in other congenital anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Neonatal mortality · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Maternal anaemia at or near term (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Maternal red blood cell folate at or near term (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Serum folate at or near term · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Intervention not reported
Reversion · People with induced SVT
1 finding from 1 review
no estimate extracted
Studies not reported
Low
Intervention not reported
Reversion · Patients presenting to emergency department with SVT
1 finding from 1 review
no estimate extracted
Studies not reported
Low
PASI score (scale range from 0 to 72 (higher score indicates more severe psoriasis)) · psoriasis
1 finding from 1 review
Quality of life (QoL) ‐ not measured · psoriasis
1 finding from 1 review
Common nuisance AEs (not leading to treatment discontinuation) · psoriasis
It is very uncertain whether FAE changes common nuisance AEs (not leading to treatment discontinuation) compared with MTX (very low certainty).
1 finding from 1 review
PASI 50 · psoriasis
It is very uncertain whether FAE changes PASI 50 compared with MTX (very low certainty).
1 finding from 1 review
Percentage of participants reaching PASI 75 · psoriasis
It is very uncertain whether FAE changes PASI 75 compared with MTX (very low certainty).
1 finding from 1 review
PASI 90 · psoriasis
It is very uncertain whether FAE changes PASI 90 compared with MTX (very low certainty).
1 finding from 1 review
Withdrawals due to adverse events · psoriasis
1 finding from 1 review
QoL · psoriasis
1 finding from 1 review
Common nuisance AEs (not leading to treatment discontinuation) · psoriasis
FAE probably leads to higher common nuisance AEs (not leading to treatment discontinuation) compared with placebo (moderate certainty).
1 finding from 1 review
PASI 50 · psoriasis
FAE may leads to higher PASI 50 compared with placebo (low certainty).
1 finding from 1 review