Healing - 1 year or longer · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether intermediate restorative material (IRM) root-end filling changes healing - 1 year or longer compared with superEBA (very low certainty).
1 finding from 1 review
Postoperative pain (VAS 0-100) - 3 days · People requiring retreatment of periapical lesions (failed root canal therapy)
Papilla base incision (PBI) led to lower postoperative pain (VAS 0-100) - 3 days compared with complete papilla mobilisation (sulcular incision); GRADE not reported.
1 finding from 1 review
Nutritional status · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)
Educational intervention with information and practical components… showed no clear difference in nutritional status compared with (Optimised) usual care; GRADE not reported.
1 finding from 1 review
OR 1.0 [0.3, 3.1]
1 study
GRADE not reported
Change in feeling of dryness · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
The review found no eligible studies for this question.
1 finding from 1 review
Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery
The review found no eligible studies for this question.
1 finding from 1 review
Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether electromagnetic radiation (low-level laser therapy) changes relief of burning/discomfort (symptom relief; pain intensity) compared with placebo (very low certainty).
1 finding from 1 review
Economic data: direct costs of materials and any reported associated indirect costs · Adults and adolescents with permanent posterior molar and premolar teeth suitable for Class I and II, but excluding Class V, amalgam…
The review found no eligible studies for this question.
1 finding from 1 review
Radiographic healing - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)
1 finding from 1 review
Angerame 2015 (7 test, 4 control): no significant difference in healing of the lesion at 1 year; significant difference only at 2- and 3-month follow-up. Small preliminary study; no robust pooled analysis.
1 study · 11 participants
GRADE not reported
Marginal integrity of restoration · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
Laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) showed no clear difference in marginal integrity of restorations compared with conventional mechanical caries removal (standard drill; handpiece…; GRADE not reported.
3 findings from 1 review
Change in taste · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
The review found no eligible studies for this question.
1 finding from 1 review
Safety of the intervention (adverse effects) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
SoF 3, Safety of the intervention over 3 months: systemic celecoxib (1 study) - 32 intervention participants reported 56 adverse effects, 20 placebo participants reported 20; 4 grade 3 events; 2 discontinued. Ketorolac…
2 studies
GRADE not reported
Oral health: Not brushing teeth twice a day · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects of pain treatment · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
RR 1.75 [0.51, 5.98]
1 study · 18 participants
GRADE not reported
RR 1.78 [0.97, 3.28]
1 study · 46 participants
GRADE not reported
RR 1.94 [1.01, 3.74]
1 study · 45 participants
Very low
Show 2 more findings
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment
Low‐level laser therapy (LLLT) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with placebo (or no irradiation); GRADE not reported.
5 findings from 1 review
MD -10.63 [-22.33, 1.07]
2 studies · 118 participants
GRADE not reported
MD -6.39 [-8.65, -4.13]
1 study · 58 participants
GRADE not reported
Two further studies (160 participants) used bespoke assessments. Harazaki 1997 (84 participants): slightly lower proportion reporting severe pain in the intervention group, no inferential statistics. Turhani 2006 (76…
2 studies · 160 participants
GRADE not reported
Show 2 more findings
MD -10.76 [-13.80, -7.73]
2 studies · 118 participants
GRADE not reported
MD -20.27 [-24.50, -16.04]
2 studies · 118 participants
Low
Leaving the study early · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
Oral health education (advice and training) showed no clear difference in leaving the study early compared with standard care (oral health advice not specifically emphasised beyond… (moderate certainty).
1 finding from 1 review
Dental state: No clinically important change in plaque index · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
It is very uncertain whether oral health education (advice and training) changes dental state: No clinically important change in plaque index compared with standard care (oral health advice not specifically emphasised beyond… (very low certainty).
1 finding from 1 review
Adverse event: tremor · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether antidepressants (trazodone 200 mg/day) changes adverse effects: tremor compared with placebo (very low certainty).
1 finding from 1 review
Healing - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether cone beam computed tomography (CBCT) preoperative evaluation changes healing - 1 year compared with conventional periapical radiography (very low certainty).
1 finding from 1 review