Tonsillectomy plus standard care vs usual care
Kidney failure · people IgA nephropathy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
4,315 questions · 23,557 findings · 2,311 reviews
No studies found 4,183 · 17.8%GRADE not reported 3,930 · 16.7%Very low 5,371 · 22.8%Low 5,787 · 24.6%Moderate 3,320 · 14.1%High 966 · 4.1%
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Tonsillectomy plus standard care vs usual care
Remission of proteinuria · people IgA nephropathy
Tonsillectomy plus standard care may leads to higher remission of proteinuria compared with standard care (low certainty).
1 finding from 1 review
- RR 1.9 [1.45, 2.47]2 studies · 143 participantsLow
Tonsillectomy plus standard care vs usual care
Remission of haematuria (microscopic) · people IgA nephropathy
Tonsillectomy plus standard care may leads to higher remission of haematuria (microscopic) compared with standard care (low certainty).
1 finding from 1 review
- RR 1.93 [1.47, 2.53]2 studies · 143 participantsLow
Tonsillectomy plus standard care vs usual care
Relapse of haematuria (macroscopic) · people IgA nephropathy
It is very uncertain whether tonsillectomy plus standard care changes relapse of haematuria (macroscopic) compared with standard care (very low certainty).
1 finding from 1 review
- RR 1.33 [0.8, 2.23]1 study · 32 participantsVery low
Renin‐angiotensin system inhibition vs placebo or no treatment
Kidney failure or doubling of SCr · people IgA nephropathy
Renin‐angiotensin system inhibition showed no clear difference in kidney failure or doubling of SCr compared with placebo or no treatment (low certainty).
1 finding from 1 review
- RR 0.25 [0.03, 2.21]1 study · 109 participantsLow
Tonsillectomy plus standard care vs usual care
Relapse of proteinuria · people IgA nephropathy
Tonsillectomy plus standard care may leads to lower relapse of proteinuria compared with standard care (low certainty).
1 finding from 1 review
- RR 0.7 [0.57, 0.85]1 study · 73 participantsLow
Tonsillectomy plus standard care vs usual care
> 50% increase in SCr · people IgA nephropathy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Tonsillectomy plus standard care vs usual care
Proteinuria · people IgA nephropathy
1 finding from 1 review
- no estimate extracted2 studies · 69 participantsLow
Renin‐angiotensin system inhibition vs placebo or no treatment
Complete remission of proteinuria · people IgA nephropathy
Renin‐angiotensin system inhibition showed no clear difference in remission of proteinuria: complete remission compared with placebo or no treatment (low certainty).
1 finding from 1 review
- RR 5.29 [0.27, 102.49]1 study · 33 participantsLow
Renin‐angiotensin system inhibition vs placebo or no treatment
Remission of haematuria · people IgA nephropathy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Renin‐angiotensin system inhibition vs placebo or no treatment
Relapse of proteinuria · people IgA nephropathy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Renin‐angiotensin system inhibition vs placebo or no treatment
> 50% increase in SCr · people IgA nephropathy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Renin‐angiotensin system inhibition vs placebo or no treatment
Proteinuria · people IgA nephropathy
1 finding from 1 review
- no estimate extracted4 studies · 199 participantsModerate
Renin‐angiotensin system inhibition vs supportive treatment
Death · people IgA nephropathy
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Renin‐angiotensin system inhibition vs supportive treatment
Kidney failure · people IgA nephropathy
It is very uncertain whether renin‐angiotensin system inhibition changes kidney failure compared with other supportive care treatment (very low certainty).
1 finding from 1 review
- RR 0.2 [0.01, 3.88]1 study · 34 participantsVery low
Angiotensin‐converting enzyme inhibitors vs placebo or no treatment
Death (all causes) · people with diabetes and kidney disease
Angiotensin‐converting‐enzyme inhibitors showed no clear difference in all‐cause death Median compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic… 2024 · Cochrane Headline outcomes onlyRR 0.91 [0.73, 1.15]24 studies · 7413 participantsLow
Angiotensin receptor blockers (ARBs) vs placebo or no treatment
Doubling of SCr Median · people with diabetes and kidney disease
Angiotensin receptor blockers may leads to lower doubling of SCr Median compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic… 2024 · Cochrane Headline outcomes onlyRR 0.84 [0.72, 0.97]4 studies · 3280 participantsLow
Angiotensin receptor blockers (ARBs) vs placebo or no treatment
Fatal or nonfatal stroke · people with diabetes and kidney disease
Angiotensin receptor blockers showed no clear difference in fatal or nonfatal stroke Median compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic… 2024 · Cochrane Headline outcomes onlyRR 0.76 [0.32, 1.77]2 studies · 619 participantsLow
Angiotensin receptor blockers (ARBs) vs placebo or no treatment
Fatal or nonfatal myocardial infarction · people with diabetes and kidney disease
Angiotensin receptor blockers showed no clear difference in fatal or nonfatal myocardial infarction Median compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic… 2024 · Cochrane Headline outcomes onlyRR 0.43 [0.11, 1.65]2 studies · 619 participantsLow
Angiotensin receptor blockers (ARBs) vs placebo or no treatment
Micro‐ to macroalbuminuria Median · people with diabetes and kidney disease
Angiotensin receptor blockers may leads to lower micro‐ to macroalbuminuria Median compared with placebo or no treatment (low certainty).
1 finding from 1 review
- Angiotensin‐converting‐enzyme inhibitors and angiotensin receptor blockers for preventing the progression of diabetic… 2024 · Cochrane Headline outcomes onlyRR 0.44 [0.23, 0.85]5 studies · 815 participantsLow