Decayed or filled primary tooth surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes decayed or filled primary tooth surfaces at 3 years compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Plaque index (PI) / oral hygiene · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review
Quality of life · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review
Normalcy of diet (tube feeding) · Adults with cancer receiving treatment
Granulocyte-macrophage colony-stimulating factor (GM-CSF) showed no clear difference in normalcy of diet (tube feeding) compared with placebo or no treatment; GRADE not reported.
1 finding from 1 review
Pre‐eclampsia · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes pre-eclampsia compared with no treatment (very low certainty).
1 finding from 1 review
Number of days in hospital · Adults receiving bone marrow/stem cell transplantation after conditioning therapy for haematological cancers
Erythropoietin mouthwash showed no clear difference in number of days in hospital compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse effects (composite: plate exposure, wound infection, sinus tract, wound dehiscence, plate removal) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomesUp to 24 months postoperatively
SoF row. Adverse effects; 60 participants (1 RCT); Quality of the evidence (GRADE): VERY LOW. Exposure of the plate: both titanium and resorbable groups experienced 2 plate exposures which occurred between the third…
1 study · 60 participants
Very low
Adverse events · Older adults with root caries in permanent (mature) teeth (mean age 75 years)
The review found no eligible studies for this question.
1 finding from 1 review
Bridge complications · Adults (18 years or older) needing a three-unit tooth-supported fixed dental prosthesis
It is very uncertain whether metal-free tooth-supported FDPs (pressed veneering ceramic) changes bridge complications compared with metal-free tooth-supported FDPs (layered veneering ceramic) (very low certainty).
1 finding from 1 review
Wound infection · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomesUp to 3 years postoperatively
The trialists did not differentiate between superficial and deep wound infection. Three (10%) of the patients in each group developed infections accounting for six plates: 3/196 (1.53%) in the titanium group and 3/165…
1 study · 60 participants
GRADE not reported
Participant experience (co-operation during procedure) · Children and adolescents with dental caries (primary teeth and permanent immature teeth)
1 finding from 1 review
Number of days of treatment with opioid analgesics · Adults with cancer receiving treatment
Keratinocyte growth factor (KGF; palifermin or repifermin),… showed no clear difference in number of days of treatment with opioid analgesics compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse events · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes adverse events compared with placebo (very low certainty).
1 finding from 1 review
Salivary flow rate · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review
Adverse events: hypotension · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Amifostine may leads to higher hypotension (adverse effect) compared with no treatment/placebo (low certainty).
1 finding from 1 review
Taste acuity improvement - objective outcome (dichotomous data) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (dichotomous data) compared with placebo (very low certainty).
1 finding from 1 review
Dysphagia (WHO grade 3+) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Biperiden plus pilocarpine showed no clear difference in dysphagia (WHO grade 3+) compared with no treatment; GRADE not reported.
1 finding from 1 review
Implant crown complications · Adults (18 years or older) with one missing tooth in the aesthetic zone needing an implant-supported single crown
It is very uncertain whether metal-free implant-supported single crowns (zirconia veneered with… changes implant crown complications compared with metal-ceramic implant-supported single crowns (very low certainty).
1 finding from 1 review
Aesthetics of the treated canine compared with the untreated contralateral canine · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
1 finding from 1 review
Adverse events · Patients with idiopathic dysgeusia and hypogeusia
The review found no eligible studies for this question.
1 finding from 1 review