NVX‐CoV2373 – Novavax vs placebo
NVX‐CoV2373 – Novavax leads to higher systemic reactogenicity eventsj compared with placebo (high certainty).
- RR 1.21 [1.17, 1.25]3 studies · 31063 participantsHigh
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NVX‐CoV2373 – Novavax leads to higher systemic reactogenicity eventsj compared with placebo (high certainty).
NVX‐CoV2373 – Novavax probably leads to higher any adverse eventm compared with placebo (moderate certainty).
NVX‐CoV2373 – Novavax showed no clear difference in serious adverse eventsm compared with placebo (low certainty).
NVX‐CoV2373 – Novavax leads to higher local reactogenicity eventsj compared with placebo (high certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.
FINLAY‐FR‐2 – Instituto Finlay de Vacunas probably leads to lower all‐cause mortalitye compared with placebo (moderate certainty).
Topical plus systemic prophylaxis leads to lower overall mortality compared with placebo or no treatment (high certainty).
Topical plus systemic prophylaxis probably leads to lower respiratory tract infections compared with placebo or no treatment (moderate certainty).
Topical plus systemic prophylaxis showed no clear difference in dropouts due to adverse events compared with placebo or no treatment (low certainty).
Topical plus systemic prophylaxis showed no clear difference in gastrointestinal adverse events compared with placebo or no treatment (low certainty).
Topical plus systemic prophylaxis showed no clear difference in allergic adverse events compared with placebo or no treatment (low certainty).
Albendazole showed no clear difference in seizure recurrence ‐ all participants compared with placebo or no anthelmintics (low certainty).
Albendazole probably leads to lower seizure recurrence ‐ participants with a single cyst compared with placebo or no anthelmintics (moderate certainty).
It is very uncertain whether albendazole changes seizure recurrence ‐ participants with multiple (> 1) cysts compared with placebo or no anthelmintics (very low certainty).
Albendazole probably leads to higher complete radiological clearance of lesions compared with placebo or no anthelmintics (moderate certainty).
Albendazole probably leads to higher evolution of cysts compared with placebo or no anthelmintics (moderate certainty).
Zinc supplementation showed no clear difference in preterm birth (< 37 weeks) compared with no zinc (with or without placebo) (low certainty).
Zinc supplementation showed no clear difference in stillbirth compared with no zinc (with or without placebo) (low certainty).