Findings

What do systematic reviews say?

3,372 questions · 3,874 findings · 666 reviews

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No studies found 431 · 11.1%GRADE not reported 783 · 20.2%Very low 995 · 25.7%Low 909 · 23.5%Moderate 596 · 15.4%High 160 · 4.1%

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Length of critical care stay (hours) · adult cardiac surgical patients

1 finding from 1 review

Fast‐track cardiac care for adult cardiac surgical patients 2016 · Cochrane Headline outcomes only
no estimate extracted
12 studies · 1394 participants
Low

Low‐dose opioid based general anaesthesia vs high‐dose opioid based general anaesthesia

Length of hospital stay · adult cardiac surgical patients

1 finding from 1 review

Fast‐track cardiac care for adult cardiac surgical patients 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 913 participants
Low

Systematic screening vs no/opportunistic screening

All‐cause mortality · general population including those at moderate to high risk of CVD, mean age between 30 and 75

Systematic screening showed no clear difference in all‐cause mortality compared with no/opportunistic screening (low certainty).

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
RR 0.98 [0.93, 1.03]
3 studies · 103571 participants
Low

Systematic screening vs no/opportunistic screening

Stroke · general population including those at moderate to high risk of CVD, mean age between 30 and 75

Systematic screening showed no clear difference in stroke (total) compared with no/opportunistic screening (low certainty).

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
RR 0.99 [0.9, 1.1]
2 studies · 79631 participants
Low

Systematic screening vs no/opportunistic screening

Total coronary heart disease · general population including those at moderate to high risk of CVD, mean age between 30 and 75

Systematic screening showed no clear difference in coronary heart disease (total) compared with no/opportunistic screening (low certainty).

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
RR 1.01 [0.95, 1.07]
4 studies · 110168 participants
Low

Systematic screening vs no/opportunistic screening

Cholesterol mg/dL · general population including those at moderate to high risk of CVD, mean age between 30 and 75

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 12591 participants
Very low

Systematic screening vs no/opportunistic screening

Systolic blood pressure · general population including those at moderate to high risk of CVD, mean age between 30 and 75

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 12591 participants
Very low

Systematic screening vs no/opportunistic screening

Diastolic blood pressure · general population including those at moderate to high risk of CVD, mean age between 30 and 75

1 finding from 1 review

Systematic versus opportunistic risk assessment for the primary prevention of cardiovascular disease 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 12591 participants
Low

Summary of findings ‐ Nipple stimulation (breast pump) vs oxytocin

Total operative and perioperative blood loss (mL) ( · a total of 87 primigravida women were enrolled, 85 completed the study: 32 were study cases and 53 were controls.28% (study group) and 22%…

1 finding from 1 review

Breastfeeding or nipple stimulation for reducing postpartum haemorrhage in the third stage of labour 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 85 participants
Low

Summary of findings ‐ Nipple stimulation (breast pump) vs oxytocin

Postnatal anaemia · a total of 87 primigravida women were enrolled, 85 completed the study: 32 were study cases and 53 were controls.28% (study group) and 22%…

1 finding from 1 review

Breastfeeding or nipple stimulation for reducing postpartum haemorrhage in the third stage of labour 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 85 participants
Low

Colchicine vs any control treatment

Mortality (all‐cause) · any patient population and people with high cardiovascular risk

Colchicine showed no clear difference in mortality (all‐cause) compared with any control treatment (moderate certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 0.94 [0.82, 1.09]
30 studies · 4174 participants
Moderate

Colchicine vs any control treatment

Cardiovascular mortality · any patient population and people with high cardiovascular risk

Colchicine showed no clear difference in mortality (cardiovascular) compared with any control treatment (moderate certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 0.34 [0.09, 1.21]
7 studies · 1132 participants
Moderate

Colchicine vs any control treatment

Myocardial infarction · any patient population and people with high cardiovascular risk

Colchicine probably leads to lower myocardial Infarction (total) compared with any control treatment (moderate certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 0.2 [0.07, 0.57]
2 studies · 652 participants
Moderate

Colchicine vs any control treatment

Adverse event (total) · any patient population and people with high cardiovascular risk

It is very uncertain whether colchicine changes adverse event (total) compared with any control treatment (very low certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 1.52 [0.93, 2.46]
11 studies · 1313 participants
Very low

Colchicine vs any control treatment

Gastrointestinal adverse events · any patient population and people with high cardiovascular risk

Colchicine may leads to higher adverse event (gastrointestinal) compared with any control treatment (low certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 1.83 [1.03, 3.26]
11 studies · 1258 participants
Low

Colchicine vs any control treatment

Adverse event (serious) · any patient population and people with high cardiovascular risk

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 472 participants
Low

Colchicine vs any control treatment

Heart failure · any patient population and people with high cardiovascular risk

Colchicine showed no clear difference in heart failure (total) compared with any control treatment (low certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
RR 0.62 [0.1, 3.88]
3 studies · 426 participants
Low

Colchicine vs any control treatment

Stroke · any patient population and people with high cardiovascular risk

Colchicine showed no clear difference in stroke (total) compared with any control treatment (low certainty).

1 finding from 1 review

Colchicine for prevention of cardiovascular events 2016 · Cochrane Headline outcomes only
OR 0.38 [0.09, 1.7]
3 studies · 874 participants
Low

Intervention not reported

Use of effective contraceptive during last sex: after year 1; 12 months after year 2 · middle or high school students with need for contraceptive information

The intervention probably leads to lower use of effective contraceptive during last sex: after year 1; 12… (moderate certainty).

1 finding from 1 review

School‐based interventions for improving contraceptive use in adolescents 2016 · Cochrane Headline outcomes only
no estimate extracted
20 participants
Moderate

Intervention not reported

Condom use at last sex: after year 1; 12 months after year 2 · middle or high school students with need for contraceptive information

The intervention probably leads to lower condom use at last sex: after year 1; 12 months after year 2 (moderate certainty).

1 finding from 1 review

School‐based interventions for improving contraceptive use in adolescents 2016 · Cochrane Headline outcomes only
no estimate extracted
20 participants
Moderate