Findings

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Evidence found and GRADE certainty

657 questions · 681 findings · 36 reviews · Oral and maxillofacial surgery

No studies found 188 · 27.6%GRADE not reported 373 · 54.8%Very low 81 · 11.9%Low 27 · 4%Moderate 8 · 1.2%High 4 · 0.6%

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Psychological status: satisfaction with life (Satisfaction With Life Scale, SWLS) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…

It is very uncertain whether maxillary distraction osteogenesis changes psychological status: satisfaction with life (Satisfaction With Life… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

1 finding from 1 review

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Maxillary advancement (midfacial hard tissue change; Subspinale A-point) · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…

It is very uncertain whether maxillary distraction osteogenesis changes maxillary advancement (midfacial hard tissue change; Subspinale… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Number of participants with postoperative bleedings requiring intervention · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA)… probably leads to lower number of participants with postoperative bleedings requiring… compared with placebo (placebo solution/mouthwash) (moderate certainty).

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Costs: direct cost of treatment · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Amount of postoperative blood loss (mL) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

The review found no eligible studies for this question.

1 finding from 1 review

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Speech: nasal emission · Adolescents or adults (15 years or older) with an established diagnosis of complete cleft lip and alveolar process, or complete unilateral…

Maxillary distraction osteogenesis showed no clear difference in speech: nasal emission compared with orthognathic surgery (conventional Le Fort I osteotomy); GRADE not reported.

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Exposure of the plate (adverse effect) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Both titanium and resorbable groups experienced two plate exposures which occurred between the third and ninth month, with plate exposure rates of 1.02% for the titanium group and 1.21% for the resorbable group. All…
    1 study · 60 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Occurrence of sinus tract (adverse effect) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Five patients (three in the titanium group and two in the resorbable group) developed a non-infected sinus tract. The sinus tracts arose earlier in the titanium group (sixth week) than in the resorbable group (third…
    1 study · 60 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Clinical stability of osteotomy segments (VAS 0 to 10) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    0 to 24 months (by period)
    Clinical stability of osteotomy segments (Cheung 2004), self-assessed on a VAS (0=very mobile, 10=no mobility) by postoperative period, titanium vs resorbable mean (SD): 0 to 2 weeks 8.10 (1.79) vs 8.47 (2.18), P=0.48;…
    1 study · 60 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Patient satisfaction (VAS 0 to 10) · Adults (>16 years old) undergoing orthognathic surgery

It is very uncertain whether resorbable (bioresorbable) plates or screws for fixation changes patient satisfaction (VAS 0 to 10) compared with titanium plates or screws for fixation (very low certainty).

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Postoperative pain during the immediate recovery period (VAS 0 to 10) · Adults (>16 years old) undergoing orthognathic surgery

It is very uncertain whether resorbable (bioresorbable) plates or screws for fixation changes postoperative pain during the immediate recovery period (VAS 0 to 10) compared with titanium plates or screws for fixation (very low certainty).

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Costs (fixation materials, hospital bed days, retreatment) · Adults (>16 years old) undergoing orthognathic surgery

The review found no eligible studies for this question.

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Re-operation and revision rate / plate removal (adverse effect) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Plate removal rates were 1.53% (3/196) of the titanium plates and 3.63% (6/165) of the resorbable ones. Out of a total of nine, two in each group were removed because of plate exposure, one patient in the titanium and…
    1 study · 60 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Status of occlusion (e.g. ANB, Angle's classification, Wits analysis) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Weidner 2005 provided analyses of mean changes in ANB from scanned radiographs. The ANB data were incomplete for many of the five time periods and were reported as 'grad' rather than the conventionally accepted…
    1 study · 43 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Need for retreatment or replacement of fixation due to failure of the fixation · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Mean 1 year
    SoF row (Resorbable plates compared to titanium plates for stabilization after orthognathic surgery). Need for retreatment or replacement of fixation due to failure of the fixation (plates failed or removed in each…
    1 study · 60 participants
    Very low

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Wound dehiscence · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Three patients (10%) in the titanium group and two patients (6.7%) in the resorbable group presented with wound dehiscence. One patient in each group with dehisced wounds became infected; all non-infected wounds closed…
    1 study · 60 participants
    GRADE not reported

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Complications: chronic wound pain · Adults (>16 years old) undergoing orthognathic surgery

It is very uncertain whether resorbable (bioresorbable) plates or screws for fixation changes postoperative chronic or lasting pain (wound discomfort) at 4 to 6… compared with titanium plates or screws for fixation (very low certainty).

1 finding from 1 review

Resorbable (bioresorbable) plates or screws for fixation vs Titanium plates or screws for fixation

Swelling (mean) · Adults (>16 years old) undergoing orthognathic surgery
1 finding from 1 review
  • Resorbable versus titanium plates for orthognathic surgery 2017 · Cochrane All outcomes
    Up to 3 years postoperatively
    Though Cheung 2004 reported the presence of postoperative swelling, it was only noted in conjunction with infection and pus discharge; assessment of this outcome did not include the use of photography or digital…
    1 study · 60 participants
    GRADE not reported