Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

309 questions · 321 findings · 28 reviews · Headline outcomes only

No studies found 45 · 14%GRADE not reported 21 · 6.5%Very low 91 · 28.3%Low 65 · 20.2%Moderate 82 · 25.5%High 17 · 5.3%

QUETIAPINE vs RISPERIDONE

Adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson medication · schizophrenia

QUETIAPINE probably leads to lower adverse effects: 2. Extrapyramidal effects ‐ use of antiparkinson… compared with RISPERIDONE (moderate certainty).

1 finding from 1 review

QUETIAPINE vs RISPERIDONE

Adverse effects: 3. Metabolic weight gain ≥7% of total body weight · schizophrenia

QUETIAPINE showed no clear difference in adverse effects: 3. Metabolic weight gain ≥7% of total body weight compared with RISPERIDONE (moderate certainty).

1 finding from 1 review