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Evidence found and GRADE certainty

1,692 questions · 2,586 findings · 180 reviews · Dental caries

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No studies found 194 · 7.5%GRADE not reported 1,937 · 74.9%Very low 248 · 9.6%Low 136 · 5.3%Moderate 52 · 2%High 19 · 0.7%

Preformed crown (any material; conventional technique or Hall Technique) vs Filling (any material; with or without complete carious tissue excavation; with or without pulp treatment)

Adverse events: gingival bleeding · Children with decayed primary molar teeth

Preformed crown (any material; conventional technique or Hall… showed no clear difference in adverse events: gingival bleeding compared with filling (any material; with or without complete carious tissue…; GRADE not reported.

2 findings from 1 review

Preformed crown (any material; conventional technique or Hall Technique) vs Filling (any material; with or without complete carious tissue excavation; with or without pulp treatment)

Satisfaction with treatment · Children with decayed primary molar teeth

The review found no eligible studies for this question.

1 finding from 1 review

Preformed crown (any material; conventional technique or Hall Technique) vs Filling (any material; with or without complete carious tissue excavation; with or without pulp treatment)

Pain · Children with decayed primary molar teeth

Preformed crown (any material; conventional technique or Hall… probably leads to lower pain compared with filling (any material; with or without complete carious tissue… (moderate certainty).

2 findings from 1 review

Preformed crown (any material; conventional technique or Hall Technique) vs No treatment

Outcome not reported · Children with decayed primary molar teeth

The review found no eligible studies for this question.

1 finding from 1 review
  • Preformed crowns for decayed primary molar teeth 2015 · Cochrane All outcomes
    Crown versus no treatment was a planned comparison (Comparison 2: crown versus no crown or filling). No study evaluated crown versus no treatment; the only study in this comparison (Santamaria 2014) used active…
    0 studies
    No studies found

Preformed crown (any material; conventional technique or Hall Technique) vs Filling (any material; with or without complete carious tissue excavation; with or without pulp treatment)

Discomfort associated with the procedure · Children with decayed primary molar teeth

Preformed crown (any material; conventional technique or Hall… probably leads to lower discomfort associated with the procedure compared with filling (any material; with or without complete carious tissue… (moderate certainty).

1 finding from 1 review

Preformed crown (any material; conventional technique or Hall Technique) vs Filling (any material; with or without complete carious tissue excavation; with or without pulp treatment)

Major failure · Children with decayed primary molar teeth
2 findings from 1 review

ART sealant using high-viscosity glass ionomer (press-finger technique) vs Resin-based sealant

Development of carious lesions on sealed occlusal pits and fissures · Children with fully erupted permanent first molar teeth (mean age about 6 to 8 years)

At 48 months, no statistically significant difference was found between HVGIC and resin-based sealants (RR 0.62, 95% CI 0.31 to 1.21); evidence ungraded and at high risk of bias.

4 findings from 1 review
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Simplified caries prediction models (>=2 predictors; microbiome-primary studies excluded), but some pooled models include microbe predictors (Yaxuan 2023: S. mutans; Kim 2018: biofilm acidogenicity/saliva) vs No competing model

Model discrimination (area under the ROC curve, AUC) · Children and adolescents aged 1-18 years

Simplified childhood caries prediction models show moderate pooled discrimination (AUC 0.79, 95% CI 0.73-0.84) but with very high heterogeneity (I2=97.3%) and all models at high risk of bias (PROBAST); ungraded.

1 finding from 1 review

Slum / urban-disadvantaged setting vs Non-slum urban / general-urban / national population

Periodontal disease prevalence · Adult residents of slums and non-slum urban settings of LMICs

Periodontal disease prevalence is high (23%-99%) across LMIC urban/slum populations; ungraded.

1 finding from 1 review

Silver diamine fluoride (SDF) vs Sealants or resin infiltration

Secondary prevention of caries · Children and adults (with or without carious lesions)

Silver diamine fluoride (SDF) showed no clear difference in secondary prevention of caries compared with sealants or resin infiltration; GRADE not reported.

1 finding from 1 review