Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

1,411 questions · 1,474 findings · 170 reviews

No studies found 336 · 22.8%GRADE not reported 97 · 6.6%Very low 419 · 28.4%Low 395 · 26.8%Moderate 188 · 12.8%High 39 · 2.6%

Summary of findings table ‐ Ibuprofen 800 mg vs prophylactic ibuprofen 800 mg women having medical abortion before 14 weeks? gestation

Patient satisfaction with abortion care overall ‐ not reported · women having medical abortion before 14 weeks' gestation

Summary of findings table ‐ Therapeutic ibuprofen 800 mg showed no clear difference in patient satisfaction with abortion care overall compared with prophylactic ibuprofen 800 mg women having medical abortion before… (low certainty).

1 finding from 1 review

Summary of findings for the main comparison: comprehensive care programmes vs usual care

Parent health, functioning, and quality of life Patient‐Reported Outcomes Measurement Information System (PROMIS) (higher scores = more of the outcome of interest, which can mean improvement or deterioration depending on the outcome) · children with medical complexity
1 finding from 1 review

Summary of findings for the main comparison: comprehensive care programmes vs usual care

Child and family satisfaction with, and perceptions of, care and service delivery Family Experiences With Coordination of Care (FECC) survey (higher scores = better) Consumer Assessment of Healthcare Providers and Systems (CAHPS) (higher scores = ... · children with medical complexity
1 finding from 1 review

Gum chewing (sugar-free) vs No chewing gum

Self-reported thirst · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

Gum chewing reduced self-reported thirst in most studies (6 of 7 positive, 1 no effect); not meta-analyzed.

1 finding from 1 review

Gum chewing (sugar-free) vs No chewing gum

Salivary flow rate · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

Across 19 studies the effect of gum chewing on stimulated and/or unstimulated salivary flow rate was mixed (9 positive, 10 no effect); this broad outcome was not meta-analyzed.

1 finding from 1 review

Gum chewing (sugar-free) vs Within-subject before/after comparison of soft gum vs hard gum (no no-gum control)

Oral mucosal moisture · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

One small study found that chewing hard (but not soft) gum increased oral mucosal moisture.

1 finding from 1 review

Daily chewing gum for 2 weeks or longer vs No gum chewing or control

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

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1 finding from 1 review

Gum chewing (sugar-free) vs No chewing gum

Salivary flow rate (unstimulated) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

In elderly and medically compromised people with xerostomia, chewing sugar-free gum daily for two or more weeks produces a small but statistically significant increase in unstimulated whole salivary flow rate versus no gum (SMD 0.44, 95% CI 0.22 to 0.66); certainty of evidence was not formally graded.

1 finding from 1 review

Gum chewing (sugar-free) vs No chewing gum

Dry mouth (xerostomia) · Elderly (>60 years) and medically compromised adults with xerostomia / dry mouth

Gum chewing was linked with improved self-reported xerostomia / dry mouth in most studies (12 of 17 positive, 5 no effect); heterogeneous instruments precluded meta-analysis.

1 finding from 1 review

Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions

Functional ability: new incidence of delirium during hospitalisation · acutely hospitalised older medical patients

It is very uncertain whether summary of findings table ‐ Rehabilitation‐related activity… changes incidence of new delirium during hospitalisation compared with usual care with or without sham interventions (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Rehabilitation‐related activity interventions vs usual care with or without sham interventions

Falls during hospitalisation · acutely hospitalised older medical patients

Summary of findings table ‐ Rehabilitation‐related activity… showed no clear difference in falls during hospitalisation compared with usual care with or without sham interventions; GRADE not reported.

1 finding from 1 review