Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
Intestinal trefoil factor (ITF), oral spray led to lower oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Adverse events · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review
Oral mucositis (moderate to severe) · Adults receiving radiotherapy to the head and neck
Granulocyte-macrophage colony-stimulating factor (GM-CSF), mouthwash showed no clear difference in oral mucositis (moderate to severe) compared with sucralfate mouthwash; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Children with acute lymphoblastic leukaemia receiving chemotherapy alone
Keratinocyte growth factor (KGF), intravenous led to lower oral mucositis (moderate to severe) compared with chlorhexidine mouthwash; GRADE not reported.
1 finding from 1 review
Oral mucositis (moderate to severe) · Children receiving bone marrow/stem cell transplantation after conditioning therapy for mixed cancers
Granulocyte-colony stimulating factor (G-CSF; pegfilgrastim, single… showed no clear difference in oral mucositis (moderate to severe) compared with granulocyte-colony stimulating factor (G-CSF; filgrastim, multiple…; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · breast cancer patients undergoing chemotherapy
Granulocyte-macrophage colony-stimulating factor (GM-CSF), higher… led to higher oral mucositis (severe) compared with granulocyte-macrophage colony-stimulating factor (GM-CSF), lower…; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Children with acute lymphoblastic leukaemia receiving chemotherapy alone
Keratinocyte growth factor (KGF), intravenous led to lower oral mucositis (severe) compared with chlorhexidine mouthwash; GRADE not reported.
1 finding from 1 review
Oral mucositis (any severity) · Adults receiving chemotherapy alone for colorectal cancer
1 finding from 1 review
Oral mucositis (any severity) · Adults receiving bone marrow/stem cell transplantation after conditioning therapy for haematological cancers
Erythropoietin mouthwash led to lower oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Number of days in hospital · Adults receiving bone marrow/stem cell transplantation after conditioning therapy for haematological cancers
Erythropoietin mouthwash showed no clear difference in number of days in hospital compared with placebo; GRADE not reported.
1 finding from 1 review
Oral mucositis (severe) · Adults receiving chemotherapy alone for colorectal cancer
Intestinal trefoil factor (ITF), oral spray showed no clear difference in oral mucositis (severe) compared with placebo; GRADE not reported.
1 finding from 1 review
Oral health assessment · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Duration of effectiveness · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Unstimulated whole saliva (UWS) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
Acupuncture may leads to higher unstimulated whole saliva (UWS) compared with placebo (sham acupuncture) (low certainty).
2 findings from 1 review
Stimulated whole saliva (SWS) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
Acupuncture may leads to higher stimulated whole saliva (SWS) compared with placebo (sham acupuncture) (low certainty).
2 findings from 1 review
Quality of life · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Dry mouth (xerostomia) · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
Acupuncture showed no clear difference in dry mouth (mouth dryness, different scales) compared with placebo (sham acupuncture) (low certainty).
1 finding from 1 review
Patient satisfaction with treatment · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Adverse events · Adults with dry mouth due to radiotherapy (head and neck cancer) or Sjogren's Syndrome
1 finding from 1 review
Acupuncture was associated with more adverse effects (tiny bruises and tiredness, mild and temporary); List 1998 noted significant eye discomfort; Pfister 2010 reported temporary increases in pain, minor bruising or…
4 studies
GRADE not reported
Dry mouth (xerostomia) · Adults seeking treatment for the symptom of dry mouth (xerostomia) due to any cause (e.g. medication, Sjogren's syndrome, radiotherapy,…
1 finding from 1 review
Donatsky 1982 (crossover, n=15, Sjogren's syndrome): CMC spray had a similar effect on oral dryness to the spray base, but was more effective than water. Paired crossover data not presented; effect size not estimable.
1 study · 15 participants
GRADE not reported