Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,971 questions · 9,849 findings · 853 reviews

No studies found 1,150 · 11.7%GRADE not reported 3,387 · 34.4%Very low 1,963 · 19.9%Low 1,809 · 18.4%Moderate 1,207 · 12.3%High 333 · 3.4%

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Endometrial resection or ablation vs unspecified (or at surgeon's discretion) route of hysterectomy

Acceptability Proportion satisfied with treatment · heavy menstrual bleeding

Endometrial resection/ablation showed no clear difference in acceptability Proportion satisfied with treatment compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs unspecified (or at surgeon's discretion) route of hysterectomy

Safety Any serious adverse event · heavy menstrual bleeding

Endometrial resection/ablation probably leads to lower safety Any serious adverse event compared with unspecified (or at surgeon's discretion) route of hysterectomy (moderate certainty).

1 finding from 1 review

Extended‐release methylphenidate vs placebo

ADHD symptoms · adults with ADHD (available evidence for participants aged between 25 to 53 years old)
3 findings from 1 review

Endometrial resection or ablation vs open hysterectomy

Effectiveness Proportion of women with perception of improvement of bleeding symptoms · HMB

Endometrial resection or ablation probably leads to lower effectiveness Woman's perception (proportion with improvement in… compared with open hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs minimally invasive hysterectomy

Acceptability Proportion satisfied with treatment · heavy menstrual bleeding

Endometrial resection or ablation probably leads to lower acceptability Proportion satisfied with treatment compared with minimally invasive hysterectomy (moderate certainty).

1 finding from 1 review

Endometrial resection or ablation vs minimally invasive hysterectomy

Requirement for further surgery for treatment failure within 1 year after surgery · heavy menstrual bleeding

Endometrial resection or ablation probably leads to higher requirement for further surgery for treatment failure within 1 year… compared with minimally invasive hysterectomy (moderate certainty).

1 finding from 1 review