Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

374 questions · 377 findings · 63 reviews · Pregnancy and Childbirth

No studies found 88 · 23.3%GRADE not reported 32 · 8.5%Very low 92 · 24.4%Low 103 · 27.3%Moderate 50 · 13.3%High 12 · 3.2%

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious neonatal morbidity or perinatal death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious neonatal morbidity/perinatal death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Vaginal PGE2 vs intravenous (IV) oxytocin

Serious maternal morbidity or death · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in serious maternal morbidity or death compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

All routine Doppler ultrasound vs no Doppler ultrasound

Stillbirth ‐ Fetal/umbilical vessels + uterine artery · Pregnant women in unselected or low‐risk populations.

All routine Doppler ultrasound showed no clear difference in stillbirth ‐ Fetal/umbilical vessels + uterine artery compared with no Doppler ultrasound (low certainty).

1 finding from 1 review

All routine Doppler ultrasound vs no Doppler ultrasound

Admission to neonatal special care unit or intensive care unit · Pregnant women in unselected or low‐risk populations.

All routine Doppler ultrasound showed no clear difference in neonatal admission to special care baby unit/neonatal intensive care… compared with no Doppler ultrasound (moderate certainty).

1 finding from 1 review

Intervention not reported

Perinatal mortality · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations

The intervention showed no clear difference in perinatal mortality (moderate certainty).

1 finding from 1 review

Intervention not reported

Preterm delivery < 37 weeks' gestation · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations

The intervention showed no clear difference in preterm delivery < 37 weeks' gestation (high certainty).

1 finding from 1 review

Intervention not reported

Induction of labour · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations

The intervention showed no clear difference in induction of labour (moderate certainty).

1 finding from 1 review

Intervention not reported

Caesarean section · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations

The intervention showed no clear difference in caesarean section (high certainty).

1 finding from 1 review

Intervention not reported

Preterm delivery less than 34 weeks · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations
1 finding from 1 review

Intervention not reported

Maternal psychological effects · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations
1 finding from 1 review

Intervention not reported

Neurodevelopment at age 2 · women in late pregnancy (after 24 weeks' gestation) in both unselected populations and designated low‐risk populations
1 finding from 1 review