Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

778 questions · 809 findings · 116 reviews

No studies found 205 · 25.3%GRADE not reported 111 · 13.7%Very low 225 · 27.8%Low 155 · 19.2%Moderate 85 · 10.5%High 28 · 3.5%

Summary of findings table ‐ Pseudophakia vs aphakia

Visual axis opacification · children younger than two years of age with bilateral congenital cataracts

It is very uncertain whether summary of findings table ‐ Pseudophakia changes visual axis opacification compared with aphakia (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Pseudophakia vs aphakia

Glaucoma at 5 years · children younger than two years of age with bilateral congenital cataracts

It is very uncertain whether summary of findings table ‐ Pseudophakia changes glaucoma at 5 years compared with aphakia (very low certainty).

1 finding from 1 review

Botulinum toxin vs placebo

Participant‐reported improvement in sialorrhea in the short term · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis

Botulinum toxin injection showed no clear difference in participant‐reported improvement in sialorrhea in the short term… compared with placebo (low certainty).

1 finding from 1 review