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Evidence found and GRADE certainty

1,057 questions · 1,077 findings · 32 reviews · Skin

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No studies found 395 · 36.7%GRADE not reported 89 · 8.3%Very low 172 · 16%Low 177 · 16.4%Moderate 191 · 17.7%High 53 · 4.9%

UVA1 vs narrowband UVB

Proportion of participants without relapse in the long term ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Etretinate vs placebo or no treatment

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants cleared or almost cleared in the short… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Etretinate vs placebo or no treatment

Proportion of participants without relapse in the long term ‐ not reported · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants without relapse in the long term (6 months) compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Etretinate vs placebo or no treatment

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants with adverse effects ‐ measured over 12… compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Etretinate with PUVA therapy as co‐intervention vs placebo with PUVA therapy

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether etretinate with PUVA therapy as co‐intervention changes proportion of participants cleared or almost cleared in the short… compared with placebo with PUVA therapy (very low certainty).

1 finding from 1 review

Etretinate with PUVA therapy as co‐intervention vs placebo with PUVA therapy

Proportion of participants with adverse effects ‐ measured over 8 weeks · chronic palmoplantar pustulosis

It is very uncertain whether etretinate with PUVA therapy as co‐intervention changes proportion of participants with adverse effects ‐ measured over 20… compared with placebo with PUVA therapy (very low certainty).

1 finding from 1 review

Etretinate vs PUVA

Proportion of participants cleared or almost cleared ‐ · chronic palmoplantar pustulosis

It is very uncertain whether etretinate changes proportion of participants cleared or almost cleared in the short… compared with PUVA therapy (very low certainty).

1 finding from 1 review

Etretinate vs PUVA

Proportion of participants with adverse effects serious or severe enough to have caused withdrawal ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review

Etretinate vs PUVA

Proportion of participants with at least 50% improvement in their quality of life ‐ not reported · chronic palmoplantar pustulosis

The review found no eligible studies for this question.

1 finding from 1 review