Major complications at the implant site · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate-delayed implants (placed within 8 weeks after tooth… led to higher major complications at the implant site compared with delayed implants (placed at least 2 months after extraction); GRADE not reported.
1 finding from 1 review
Pain on TMJ palpation (ordinal scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in pain on TMJ palpation (ordinal scale) compared with placebo; GRADE not reported.
1 finding from 1 review
Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
Withdrawals due to adverse events · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
Four of the participants withdrew from the study by Kimos et al 2007 due to adverse effects, but neither the type of adverse effect nor the trial group was specified.
1 study · 44 participants
GRADE not reported
Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Bio-Oss (anorganic bovine bone) showed no clear difference in bone gain (horizontal - HDD) compared with bio-Oss + resorbable barrier; GRADE not reported.
1 finding from 1 review
Adverse events (reported; mild, no withdrawals) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
Roldan et al 1990 (diazepam) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse effects were…
1 study · 41 participants
GRADE not reported
Change in pain index · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral propranolol (beta-blocker) showed no clear difference in change in pain index compared with placebo; GRADE not reported.
1 finding from 1 review
Vertical bone gain · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Non-resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (vertical - VDH) compared with resorbable barrier + autogenous bone; GRADE not reported.
1 finding from 1 review
All treatments resulted in statistically significant bone gain, however no statistically significant differences were found between the three procedures (Chen 2005a). Vertical height of the defect (VDH).
1 study · 25 participants
GRADE not reported
Adverse events (reported; mild, no withdrawals) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
1 finding from 1 review
Ekberg et al 1996 (diclofenac) reported adverse effects. Per the review's Adverse effects of interventions section: 'All but one study (Lobo et al 2004) reported adverse effects. Most of the reported adverse effects…
1 study · 32 participants
GRADE not reported
Participants' assessment of improvement of pain in right TMJ (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral clonazepam (benzodiazepine) showed no clear difference in participants' assessment of improvement of pain in right TMJ (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
No improvement in TMJ pain on external palpation · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral prazepam (benzodiazepine) showed no clear difference in no improvement in TMJ pain on external palpation compared with placebo; GRADE not reported.
2 findings from 1 review
Pain on palpation of right masseter muscle (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral clonazepam (benzodiazepine) showed no clear difference in pain on palpation of right masseter muscle (VAS) compared with placebo; GRADE not reported.
1 finding from 1 review
Bone gain (horizontal - HDD) · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Non-resorbable barrier (guided bone regeneration) showed no clear difference in bone gain (horizontal - HDD) compared with resorbable barrier + autogenous bone; GRADE not reported.
1 finding from 1 review
All treatments resulted in statistically significant bone gain, however no statistically significant differences were found between the three procedures (Chen 2005a). Horizontal depth of the defect (HDD).
1 study · 25 participants
GRADE not reported
Marginal bone level change · Patients with compromised teeth to be extracted who require single dental implants in fresh postextraction sockets
Immediate implants (placed in a fresh extraction socket just after… showed no clear difference in perimplant marginal bone level changes compared with delayed implants (placed at least 2 months after extraction, in…; GRADE not reported.
1 finding from 1 review
Prosthesis failure · Patients receiving immediate single implants in fresh extraction sockets (maxillary anterior/premolar sites)
Autogenous bone graft augmentation at the immediate implant site led to lower prosthesis failure compared with no augmentation; GRADE not reported.
1 finding from 1 review
In total two implants were lost in the autogenous bone group, whereas no complications or failures occurred in the non-augmented control group; underpowered, no statistically significant difference (Chen 2005b).
1 study · 26 participants
GRADE not reported
No improvement in spontaneous TMJ pain · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral prazepam (benzodiazepine) showed no clear difference in no improvement in spontaneous TMJ pain compared with placebo; GRADE not reported.
2 findings from 1 review
Spontaneous masseter muscle pain (numerical graph rating scale) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Topical methyl salicylate (Theraflex-TMJ) led to lower spontaneous masseter muscle pain (numerical graph rating scale) compared with placebo; GRADE not reported.
1 finding from 1 review
Spontaneous pain in the TMJ (VAS) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Topical methyl salicylate (Theraflex-TMJ) led to lower spontaneous TMJ pain (numerical graph rating scale) compared with placebo; GRADE not reported.
1 finding from 1 review
Total pain rating index (McGill Pain Questionnaire) · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral glucosamine hydrochloride/chondroitin sulphate showed no clear difference in total pain rating index (McGill Pain Questionnaire) compared with placebo; GRADE not reported.
1 finding from 1 review
No improvement in TMJ pain during mastication · Adult patients aged >=18 years, clinically or radiographically diagnosed with TMD (McNeill 1997 criteria); moderate to severe pain of…
Oral prazepam (benzodiazepine) showed no clear difference in no improvement in TMJ pain during mastication compared with placebo; GRADE not reported.
2 findings from 1 review