Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

405 questions · 407 findings · 32 reviews · Airways

No studies found 31 · 7.6%GRADE not reported 25 · 6.1%Very low 27 · 6.6%Low 122 · 30%Moderate 148 · 36.4%High 54 · 13.3%

ICS dose reduction vs no change

Rate of exacerbations requiring systemic corticosteroids · adults with asthma

It is very uncertain whether ICS dose reduction changes exacerbation requiring OCS compared with no change (very low certainty).

2 findings from 1 review

ICS dose reduction vs no change

SAEs · adults with asthma

ICS dose reduction showed no clear difference in all‐cause SAEs compared with no change (low certainty).

2 findings from 1 review