Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Electronic caries monitor (ECM) device (ECM II / ECM III / ECM IV) vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
1 finding from 1 review
  • Electrical conductance for the detection of dental caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies)
    ECM (4 studies, 475 tooth surfaces): sensitivity ranged from 0.61 to 0.98 (0.61-0.65 in three studies; 0.98 in the most recent ECM IV study). No evidence of a difference in accuracy by device type (Chi2=0.05, df=1,…
    4 studies
    GRADE not reported

Electronic caries monitor (ECM) device (ECM II / ECM III / ECM IV) vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
1 finding from 1 review

CarieScan Pro device vs Reference standard (histology, excavation, or enhanced visual examination)

Specificity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
1 finding from 1 review

Intervention not reported

Cohort studies ‐ 1 dose · children 9 months to 15 years old

The intervention probably leads to lower cohort studies ‐ 1 dose (moderate certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ Jeryl Lynn strain ‐ household contacts · children 9 months to 15 years old

The intervention probably leads to lower cohort studies ‐ Jeryl Lynn strain ‐ household contacts (moderate certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ encephalitis meningitis ‐ encephalitis meningitis risk period (0 to 90 days) · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series ‐ encephalitis meningitis ‐ encephalitis… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ herpes ‐ herpes risk period (0 to 90 days) · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series ‐ herpes ‐ herpes risk period (0 to 90… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ pneumonia ‐ pneumonia risk period (0 to 90 days) · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series ‐ pneumonia ‐ pneumonia risk period (0… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ miscellaneous viral infections ‐ miscellaneous viral infections risk period (0 to 90 days) · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series ‐ miscellaneous viral infections ‐… (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ Urabe strain ‐ unspecified numbers or at least 1 dose · children 9 months to 15 years old

The intervention may leads to lower cohort studies ‐ Urabe strain ‐ unspecified numbers or at least 1 dose (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ Rubini strain ‐ unspecified numbers or at least 1 dose · children 9 months to 15 years old

The intervention showed no clear difference in cohort studies ‐ Rubini strain ‐ unspecified numbers or at least 1… (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ mumps strain not reported or any strain · children 9 months to 15 years old

The intervention may leads to lower cohort studies ‐ mumps strain not reported or any strain (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ third dose versus 2 doses · children 9 months to 15 years old

The intervention showed no clear difference in cohort studies ‐ third dose versus 2 doses (low certainty).

1 finding from 1 review

Intervention not reported

Cohort studies secondary cases ‐ any strain · children 9 months to 15 years old

The intervention probably leads to lower cohort studies secondary cases ‐ any strain (moderate certainty).

1 finding from 1 review

Intervention not reported

MMRV randomised controlled trial ‐ any severity ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMRV randomised controlled trial ‐ any severity ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMRV randomised controlled trial ‐ any severity ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMRV randomised controlled trial ‐ any severity ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMRV randomised controlled trial ‐ any severity ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMRV randomised controlled trial ‐ any severity ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

MMRV randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMRV randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ (high certainty).

1 finding from 1 review

Intervention not reported

Cohort studies ‐ 2 doses · children 9 months to 15 years old

The intervention probably leads to lower cohort studies ‐ 2 doses (moderate certainty).

1 finding from 1 review

Intervention not reported

MMRV randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ · children 9 months to 15 years old

The intervention leads to lower MMRV randomised controlled trial ‐ moderate/severe cases ‐ 2 doses ‐ (high certainty).

1 finding from 1 review