Aesthetics · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
The review found no eligible studies for this question.
1 finding from 1 review
Dental pain or sensitivity · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes dental pain or sensitivity compared with fluoride varnish (very low certainty).
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Ruff 2022 reported that there were no adverse events during the study period; adverse events were not defined by the study authors. Assumed data available for 1398 participants.
1 study · 1398 participants
Very low
Caries arrest · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes caries arrest compared with restoration (restorative treatment) (very low certainty).
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Adverse effects · Children and adults (with or without carious lesions)
1 finding from 1 review
Gao 2019 noted that "arrested lesions were stained black" (reported with no associated data). No other adverse effects observed, and no reports from parents of systemic disease.
1 study · 1070 participants
Very low
Dental pain or sensitivity · Children and adults (with or without carious lesions)
It is very uncertain whether silver diamine fluoride (SDF) changes dental pain or sensitivity compared with restoration (restorative treatment) (very low certainty).
1 finding from 1 review
Intervention not reported
Reulceration · people with healed venous leg ulcers
The intervention showed no clear difference in reulceration (low certainty).
1 finding from 1 review
Intervention not reported
Duration of reulceration episodes · people with healed venous leg ulcers
1 finding from 1 review
no estimate extracted
1995 participants
GRADE not reported
Intervention not reported
Proportion of · people with healed venous leg ulcers
1 finding from 1 review
no estimate extracted
1995 participants
GRADE not reported
Intervention not reported
Ulceration on the contralateral leg · people with healed venous leg ulcers
1 finding from 1 review
no estimate extracted
1995 participants
GRADE not reported
Intervention not reported
Noncompliance · people with healed venous leg ulcers
The intervention showed no clear difference in noncompliance (low certainty).
1 finding from 1 review
Intervention not reported
Comfort · people with healed venous leg ulcers
1 finding from 1 review
no estimate extracted
1995 participants
GRADE not reported
Intervention not reported
Adverse effects · people with healed venous leg ulcers
1 finding from 1 review
no estimate extracted
1995 participants
GRADE not reported
Gastrointestinal adverse events · patients (> 65 years) following hip fracture; patients with a recent stroke
It is very uncertain whether summary of findings table ‐ Protein changes side effects: at least one adverse gastrointestinal event compared with standard diet (very low certainty).
1 finding from 1 review
Costs ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Health‐related quality of life ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Acceptability of nutritional supplements ‐ not reported · patients (> 65 years) following hip fracture; patients with a recent stroke
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Clinical vertebral fractures · postmenopausal women at lower risk of fractures1
Intermittent/cyclic etidronate 400 mg/day showed no clear difference in clinical vertebral fractures compared with placebo (low certainty).
1 finding from 1 review
RR 3.03 [0.32, 28.44]
Studies not reported
Low