Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,006 questions · 3,171 findings · 607 reviews · Headline outcomes only

No studies found 411 · 13%GRADE not reported 153 · 4.8%Very low 968 · 30.5%Low 897 · 28.3%Moderate 589 · 18.6%High 153 · 4.8%

Procedures: doffing with double gloves vs doffing with single gloves

Contamination with fluorescent · healthcare workers

It is very uncertain whether procedures: doffing with double gloves changes contamination with fluorescent compared with doffing with single gloves (very low certainty).

1 finding from 1 review

Procedures: donning and doffing with instructions vs No special instructions (control)

People with one or more errors · healthcare workers

It is very uncertain whether procedures: donning and doffing with instructions changes people with one or more errors compared with without instruction (very low certainty).

1 finding from 1 review

Procedures: doffing with extra sanitation of gloves vs standard no sanitation

Bacterial contamination: alcohol‐based hand rub · healthcare workers

Procedures: doffing with extra sanitation of gloves showed no clear difference in bacterial contamination: alcohol‐based hand rub compared with standard no sanitation (low certainty).

1 finding from 1 review

Procedures: doffing with hypochlorite vs doffing with alcohol‐based glove sanitiser

Contamination: MS2 · healthcare workers

It is very uncertain whether procedures: doffing with hypochlorite changes contamination: MS2 compared with doffing with alcohol‐based glove sanitiser (very low certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy probably leads to lower mortality at 6 months compared with medical treatment only (moderate certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Mortality at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy leads to lower mortality at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol at 6 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy may leads to higher 'Unfavorable outcome' as per original Cochrane protocol at 6 months compared with medical treatment only (low certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in 'Unfavorable outcome' as per original Cochrane protocol ‐ at 12 months compared with medical treatment only (high certainty).

1 finding from 1 review

Decompressive craniectomy vs medical treatment

Changes in ICP from randomization up to 48 h · patients > 12 months of age with a severe traumatic brain injury and in a coma (post‐resuscitation GOS score ≤ 8 points) with raised,…

Decompressive craniectomy showed no clear difference in changes in ICP from randomization up to 48 h compared with medical treatment only (moderate certainty).

1 finding from 1 review