Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,808 questions · 8,953 findings · 827 reviews · Headline outcomes only

No studies found 1,891 · 21.1%GRADE not reported 380 · 4.2%Very low 2,100 · 23.5%Low 2,449 · 27.4%Moderate 1,684 · 18.8%High 449 · 5%

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Sunlight (with or without filters or amplification) vs other sources of phototherapy

Treatment failure requiring exchange transfusionc,d · infants with confirmed hyperbilirubinemia

Sunlight (with or without filters or amplification) showed no clear difference in treatment failure requiring exchange transfusionc,d compared with other sources of phototherapy (low certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Acute bilirubin encephalopathy · infants with confirmed hyperbilirubinemia

Sunlight (with or without filters or amplification) may leads to lower acute bilirubin encephalopathyc,f compared with other sources of phototherapy (low certainty).

1 finding from 1 review

Sunlight (with or without filters or amplification) vs other sources of phototherapy

Proportion of days of effective treatmenti · infants with confirmed hyperbilirubinemia

It is very uncertain whether sunlight (with or without filters or amplification) changes proportion of days of effective treatmenti compared with other sources of phototherapy (very low certainty).

1 finding from 1 review

Azathioprine vs cyclophosphamide

Relapse · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in relapse at 18 months compared with cyclophosphamide (moderate certainty).

2 findings from 1 review

Azathioprine vs cyclophosphamide

Serious adverse events · adults with renal vasculitis for maintenance therapy

Azathioprine showed no clear difference in serious adverse events compared with cyclophosphamide (moderate certainty).

1 finding from 1 review