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Vibrational appliance with fixed appliances showed no clear difference in time to alignment (days) compared with fixed appliances only / no vibrational appliance (control); GRADE not reported.
Antibiotics probably leads to lower sore throat: day 3 compared with control (moderate certainty).
Antibiotics showed no clear difference in fever: day 3 compared with control (high certainty).
Antibiotics leads to lower headache: day 3 compared with control (high certainty).
Antibiotics probably leads to lower rheumatic fever (within 2 months, clinical diagnosis) compared with control (moderate certainty).
Antibiotics showed no clear difference in glomerulonephritis (within 1 month, clinical diagnosis) compared with control (low certainty).
Antibiotics leads to lower quinsy (within 2 months, clinical diagnosis) compared with control (high certainty).
Antibiotics leads to lower otitis media (within 14 days, clinical diagnosis) compared with control (high certainty).
Summary of findings table ‐ Anticoagulant showed no clear difference in dead or dependent at end of compared with control (high certainty).
Summary of findings table ‐ Anticoagulant showed no clear difference in death from all causes during treatment period compared with control (low certainty).
It is very uncertain whether summary of findings table ‐ Anticoagulant changes deep vein thrombosis during treatment period compared with control (very low certainty).
Summary of findings table ‐ Anticoagulant probably leads to lower recurrent ischaemic or unknown stroke during treatment period compared with control (moderate certainty).
Summary of findings table ‐ Anticoagulant probably leads to higher symptomatic intracranial haemorrhage during treatment period compared with control (moderate certainty).
Summary of findings table ‐ Anticoagulant leads to lower symptomatic pulmonary embolism during treatment period compared with control (high certainty).
Summary of findings table ‐ Anticoagulant probably leads to higher major extracranial haemorrhage during treatment period compared with control (moderate certainty).
It is very uncertain whether morphine changes treatment failure To discharge compared with buprenorphine (very low certainty).
It is very uncertain whether morphine changes seizures To discharge compared with buprenorphine (very low certainty).
The review found no eligible studies for this question.
The review found no eligible studies for this question.