Findings

What do systematic reviews say?

4,072 questions · 4,237 findings · 447 reviews · Headline outcomes only

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No studies found 946 · 22.3%GRADE not reported 257 · 6.1%Very low 1,121 · 26.5%Low 1,207 · 28.5%Moderate 568 · 13.4%High 138 · 3.3%

Intervention not reported

D2 receptor antagonists · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 participants
GRADE not reported

Intervention not reported

Amisulpride (2 RCTs; 904 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 904 participants
Low

Intervention not reported

Droperidol (22 RCTs; 3679 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 3679 participants
Moderate

Intervention not reported

Haloperidol (2 RCTs; 99 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 99 participants
Low

Intervention not reported

Metoclopramide (11 RCTs; 1313 participants) · adults undergoing any type of surgery under general anaesthesia Interventions: antiemetic drugs (monoprophylaxis and combination…

1 finding from 1 review

Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta‐analysis 2020 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1313 participants
Very low

Transverse groin incision vs vertical groin incision

Surgical site infection · patients undergoing surgery with femoral artery approach

Transverse groin incision may leads to lower surgical site infection (10 to 28 days) compared with vertical groin incision (low certainty).

1 finding from 1 review

Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes only
RR 0.25 [0.08, 0.76]
1 study · 283 participants
Low

Transverse groin incision vs vertical groin incision

Lymphatic complications: Lymphatic leak (28 days) Lymphatic collection (28 days) · patients undergoing surgery with femoral artery approach

It is very uncertain whether transverse groin incision changes lymphatic complications: Lymphatic leak (28 days) Lymphatic… compared with vertical groin incision (very low certainty).

1 finding from 1 review

Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes only
RR 0.46 [0.2, 1.02]
116 participants
Very low

Transverse groin incision vs vertical groin incision

Graft infection · patients undergoing surgery with femoral artery approach

The review found no eligible studies for this question.

1 finding from 1 review

Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transverse groin incision vs vertical groin incision

Prolonged hospitalization (> 1 week) · patients undergoing surgery with femoral artery approach

The review found no eligible studies for this question.

1 finding from 1 review

Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transverse groin incision vs vertical groin incision

Death · patients undergoing surgery with femoral artery approach

The review found no eligible studies for this question.

1 finding from 1 review

Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Transverse groin incision vs vertical groin incision

Neurological deficit (e.g. paresthesia) · patients undergoing surgery with femoral artery approach

The review found no eligible studies for this question.

1 finding from 1 review

Transverse versus vertical groin incision for femoral artery approach 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS –lidocaine vs bupivacaine · adults undergoing surgery

Risk of transient neurological symptoms with spinal lidocaine probably leads to lower presence of any TNS –lidocaine vs bupivacaine compared with other local anaesthetic (moderate certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 0.16 [0.09, 0.28]
12 studies · 1220 participants
Moderate

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS – lidocaine vs 2‐chloroprocaine · adults undergoing surgery

Risk of transient neurological symptoms with spinal lidocaine showed no clear difference in presence of any TNS – lidocaine vs 2‐chloroprocaine compared with other local anaesthetic (low certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 0.09 [0.01, 1.51]
2 studies · 94 participants
Low

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS – lidocaine vs levobupivacaine · adults undergoing surgery

Risk of transient neurological symptoms with spinal lidocaine may leads to lower presence of any TNS – lidocaine vs levobupivacaine compared with other local anaesthetic (low certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 0.13 [0.02, 0.69]
2 studies · 120 participants
Low

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS – lidocaine vs mepivacaine · adults undergoing surgery

It is very uncertain whether risk of transient neurological symptoms with spinal lidocaine changes presence of any TNS – lidocaine vs mepivacaine compared with other local anaesthetic (very low certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 1.01 [0.18, 5.82]
4 studies · 274 participants
Very low

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS – lidocaine vs prilocaine · adults undergoing surgery

Risk of transient neurological symptoms with spinal lidocaine probably leads to lower presence of any TNS – lidocaine vs prilocaine compared with other local anaesthetic (moderate certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 0.18 [0.07, 0.49]
4 studies · 429 participants
Moderate

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS – lidocaine vs procaine · adults undergoing surgery

Risk of transient neurological symptoms with spinal lidocaine probably leads to lower presence of any TNS – lidocaine vs procaine compared with other local anaesthetic (moderate certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 0.14 [0.04, 0.52]
2 studies · 130 participants
Moderate

Risk of transient neurological symptoms with spinal lidocaine vs other local anaesthetic

Presence of any TNS – lidocaine vs ropivacaine · adults undergoing surgery

Risk of transient neurological symptoms with spinal lidocaine may leads to lower presence of any TNS – lidocaine vs ropivacaine compared with other local anaesthetic (low certainty).

1 finding from 1 review

Transient neurological symptoms (TNS) following spinal anaesthesia with lidocaine versus other local anaesthetics in… 2019 · Cochrane Headline outcomes only
RR 0.1 [0.01, 0.78]
2 studies · 90 participants
Low

Bispectral index vs clinical signs

Time to eye opening · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Bispectral index for improving intraoperative awareness and early postoperative recovery in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 1494 participants
Low

Bispectral index vs clinical signs

Time to orientation · adults undergoing surgery with general anaesthesia

1 finding from 1 review

Bispectral index for improving intraoperative awareness and early postoperative recovery in adults 2019 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 273 participants
Low