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Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,050 questions in 42 reviews · Incontinence

current versions
No studies 391 · 37.2%Ungraded 82 · 7.8%Very low 199 · 19%Low 206 · 19.6%Moderate 150 · 14.3%High 22 · 2.1%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Low intensity ES plus PFMT vs maximal intensity ES plus PFMT
Adverse effects ‐ not reported · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extractedNRNo studies
Electrical stimulation vs no active treatment
Cost‐effectiveness · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extractedNRNo studies
Low intensity ES plus PFMT vs maximal intensity ES plus PFMT
Cost‐effectiveness ‐ not reported · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extractedNRNo studies
Conventional ES plus PFMT vs dynamic ES plus PFMT
Cure: number of women with self‐reported continence · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extractedNRNo studies
Conventional ES plus PFMT vs dynamic ES plus PFMT
Improvement: number of women with self‐reported improvement in SUI (cured or improved) (perception of bother of UI symptoms) · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Conventional ES plus PFMT vs dynamic ES plus PFMT
Incontinence‐specific quality of life · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extracted1 study · 61 participantsVery low
Conventional ES plus PFMT vs dynamic ES plus PFMT
Adverse effects ‐ not reported · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extractedNRNo studies
Conventional ES plus PFMT vs dynamic ES plus PFMT
Cost‐effectiveness ‐ not reported · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extractedNRNo studies
Electrical stimulation vs sham treatment
Cure: number of women with self‐reported continence · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
RR 2.21 [0.38, 12.73]3 studies · 158 participantsVery low
Electrical stimulation vs sham treatment
Improvement: number of women with self‐reported improvement in SUI (cured or improved) · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
RR 2.03 [1.02, 4.07]5 studies · 236 participantsLow
Electrical stimulation vs sham treatment
Incontinence‐specific quality of life · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
no estimate extracted2 studies · 117 participantsLow
Electrical stimulation vs sham treatment
Adverse effects · women with stress urinary incontinence
Electrical stimulation with non‐implanted devices for stress urinary incontinence in women (2017) · Cochrane
RR 2.01 [0.52, 7.67]4 studies · 233 participantsLow
Tricyclics vs placebo
Number of wet nights per week at the end of treatment ‐ imipramine vs placebo · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted4 studies · 347 participantsVery low
Tricyclics vs another drug
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs desmopressin + oxybutynin · Children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 2.39 [1.35, 4.25]1 study · 45 participantsVery low
Tricyclics vs another drug
Adverse events assessed as reported in paper · Children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted9 studies · 9 participantsVery low
Tricyclics vs behavioural interventions
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs alarm · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 4 [1.06, 15.08]1 study · 24 participantsVery low
Tricyclics vs behavioural interventions
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs alarm (Mozes detector) · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 1.28 [1.07, 1.53]2 studies · 184 participantsVery low
Tricyclics vs behavioural interventions
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs 3 step therapy (reassurance, retention control training + wakening, parental involvement) · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 1.83 [1.08, 3.12]1 study · 72 participantsLow
Tricyclics vs behavioural interventions
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs 3 step therapy + motivation/counselling + education · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 3.91 [2.3, 6.66]1 study · 132 participantsLow
Tricyclics vs behavioural interventions
Number not achieving 14 consecutive dry nights or relapsing at · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 1.67 [1.03, 2.69]1 study · 24 participantsVery low
Tricyclics vs behavioural interventions
Number not achieving 14 consecutive dry nights or relapsing at · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 3.56 [2.21, 5.72]1 study · 132 participantsLow
Tricyclics vs behavioural interventions
Adverse events assessed as reported in paper · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted4 studies · 4 participantsVery low
Intervention NR
Number of wet nights per week at the end of treatment ‐ imipramine + oxybutynin vs imipramine · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted1 study · 63 participantsVery low
Tricyclics vs placebo
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs placebo · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 0.74 [0.61, 0.9]12 studies · 831 participantsVery low
Intervention NR
Number of wet nights per week at the end of treatment ‐ Amitriptyline + desmopressin vs amitriptyline · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted1 study · 28 participantsVery low
Intervention NR
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine + oxybutynin vs placebo · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 0.43 [0.23, 0.78]1 study · 47 participantsModerate
Intervention NR
Adverse events assessed as reported in paper · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted2 studies · 2 participantsModerate
Tricyclics vs placebo
Number not achieving 14 consecutive dry nights at the end of treatment ‐ amitriptyline vs placebo · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 0.83 [0.72, 0.97]2 studies · 98 participantsLow
Tricyclics vs placebo
Number of wet nights per week at · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted1 study · 21 participantsVery low
Tricyclics vs placebo
Number not achieving 14 consecutive dry nights or relapsing at · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 0.99 [0.95, 1.03]5 studies · 416 participantsLow
Tricyclics vs placebo
Adverse events assessed as reported in paper · children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted18 studies · 56 participantsVery low
Tricyclics vs another drug
Number of wet nights per week at the end of treatment ‐ imipramine vs desmopressin · Children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted3 studies · 300 participantsVery low
Tricyclics vs another drug
Number of wet nights per week at the end of treatment ‐ amitriptyline vs desmopressin · Children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
no estimate extracted1 study · 31 participantsVery low
Tricyclics vs another drug
Number not achieving 14 consecutive dry nights at the end of treatment ‐ imipramine vs desmopressin · Children with nocturnal enuresis
Tricyclic and related drugs for nocturnal enuresis in children (2016) · Cochrane
RR 0.88 [0.64, 1.2]4 studies · 222 participantsVery low
Electrical stimulation vs no active treatment
Participants cured or improved · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
RR 1.85 [1.34, 2.55]2 studies · 121 participantsLow
Electrical stimulation vs pelvic floor muscle training (PFMT)
Participants with improvement in urgency urinary incontinence · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
RR 1.62 [0.51, 5.12]1 study · 52 participantsVery low
Electrical stimulation vs pelvic floor muscle training (PFMT)
OAB‐related quality of life · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted1 study · 49 participantsVery low
Electrical stimulation vs pelvic floor muscle training (PFMT)
Adverse effects · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs pelvic floor muscle training (PFMT) plus biofeedback
Participants cured or improved · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs pelvic floor muscle training (PFMT) plus biofeedback
Participants with improvement in urgency urinary incontinence · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
RR 1.06 [0.6, 1.85]1 study · 51 participantsLow
Electrical stimulation vs pelvic floor muscle training (PFMT) plus biofeedback
OAB‐related quality of life · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted1 study · 51 participantsLow
Electrical stimulation vs pelvic floor muscle training (PFMT) plus biofeedback
Adverse effects · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs magnetic stimulation
Participants cured or improved · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs magnetic stimulation
Participants with improvement in urgency urinary incontinence · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs magnetic stimulation
OAB‐related quality of life · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs no active treatment
Participants with improvement in urgency urinary incontinence · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs magnetic stimulation
Adverse effects · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted1 study · 32 participantsVery low
Electrical stimulation vs laseropuncture/electro‐acupuncture
Participants cured or improved · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs laseropuncture/electro‐acupuncture
Participants with improvement in urgency urinary incontinence · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted0 studies · 0 participantsUngraded
Electrical stimulation vs laseropuncture/electro‐acupuncture
OAB‐related quality of life · Adults with overactive bladder (OAB)
Electrical stimulation with non‐implanted electrodes for overactive bladder in adults (2016) · Cochrane
no estimate extracted1 study · 22 participantsLow