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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

664 questions in 25 reviews · Endodontics and dental trauma

current versions
No studies 111 · 16.7%Ungraded 417 · 62.8%Very low 69 · 10.4%Low 50 · 7.5%Moderate 16 · 2.4%High 1 · 0.2%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Cast post and core with a diaphragm vs Cast post and core without a diaphragm
Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
No included trial evaluated the presence of a diaphragm in cast posts (a planned secondary comparison); no eligible study identified.0 studiesNo studies
Dycal (calcium hydroxide material) vs Cavitec (zinc oxide eugenol material)
Clinical symptoms at 12 months · Adults (aged 20 to 60 years, mean 27) with deep carious lesions in permanent teeth (indirect or direct pulp capping,… · 12 months, Complete caries removal
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Analysis 2.2 (clinical symptoms at 12 months following complete caries removal, Dycal vs Cavitec). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth…1 study · 151 participantsUngraded
Calcium hydroxide vs Zinc oxide eugenol
Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures · 24 months
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…1 study · 275 participantsUngraded
Life (calcium hydroxide material) vs Cavitec (zinc oxide eugenol material)
Clinical symptoms at 12 months · Adults (aged 20 to 60 years, mean 27) with deep carious lesions in permanent teeth (indirect or direct pulp capping,… · 12 months, Complete caries removal
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Analysis 2.2 (clinical symptoms at 12 months following complete caries removal, Life vs Cavitec). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth…1 study · 151 participantsUngraded
Life (calcium hydroxide pulp-capping material) vs Dycal (calcium hydroxide pulp-capping material)
Clinical symptoms at 12 months · Adults (aged 20 to 60 years, mean 27) with deep carious lesions in permanent teeth (indirect or direct pulp capping,… · 12 months, Complete caries removal
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Analysis 2.2 (clinical symptoms at 12 months following complete caries removal, Life vs Dycal). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth…1 study · 151 participantsUngraded
Potassium nitrate/dimethyl isosorbide/polycarboxylate cement (KNO3/DMI/PCa) vs Polycarboxylate cement (PCa) alone
Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · Adults with asymptomatic vital pulpal exposures from caries · 24 months
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Hodosh 2003 (Analysis 3.1): all 18 patients receiving KNO3/DMI/PCa responded favourably (0/18 developed clinical symptoms) versus 10/12 in the PCa group. "The results in groups two and three were statistically…1 study · 30 participantsUngraded
Glycerrhetinic acid/antibiotic mixture vs Zinc oxide eugenol
Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures · 24 months
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…1 study · 275 participantsUngraded
Post and core restoration with a ferrule vs Post and core restoration without a ferrule
Outcome NR · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · Minimum 6 months (planned)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
No included trial evaluated the presence of a ferrule (a planned secondary comparison); no eligible study identified.0 studiesNo studies
Non-metal carbon-fibre post and core (Category III; Composipost) vs Metal custom-cast post and core (Category I; gold alloy)
Clinical/technical failure (root fracture) · Participants with permanent endodontically-treated (root-filled) teeth for which a post is indicated to retain the… · 48 months (4 years)
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
RR 0.05 [0.00, 0.90]1 study · 195 participantsUngraded
Potassium nitrate/polycarboxylate cement (KNO3/PCa) vs Polycarboxylate cement (PCa) alone
Clinical success (absence of periapical pathology, tenderness to pressure and fistula formation) at 24 months · Adults with asymptomatic vital pulpal exposures from caries · 24 months
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Hodosh 2003 (Analysis 3.1): 9/17 in the KNO3/PCa group and 10/12 in the PCa group developed clinical symptoms requiring endodontic therapy or extraction. No significance test reported for this specific contrast; no…1 study · 29 participantsUngraded
Life (calcium hydroxide pulp-capping material) vs Dycal (calcium hydroxide pulp-capping material)
Clinical symptoms at 12 months · Adults (aged 20 to 60 years, mean 27) with deep carious lesions in permanent teeth (indirect or direct pulp capping,… · 12 months, Indirect pulp capping
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Analysis 2.1 (clinical symptoms at 12 months following indirect pulp capping, Life vs Dycal). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth lost…1 study · 151 participantsUngraded
Direct composite restoration (final restoration) vs Full-coverage metal-ceramic crown
Clinical failure (post dislodgement) · Participants with endodontically-treated permanent premolars restored with a carbon-fibre post (Category III) · 36 months (3 years); dislodgement assessed at 24 months
Root canal posts for the restoration of root filled teeth (2007) · Cochrane
RR 1.85 [0.17, 19.8]1 study · 104 participantsUngraded
Ledermix (corticosteroid/antibiotic pulp-capping cement) vs Zinc oxide eugenol
Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures · 24 months
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…1 study · 275 participantsUngraded
Life (calcium hydroxide pulp-capping material) vs Dycal (calcium hydroxide pulp-capping material)
Clinical symptoms at 12 months · Adults (aged 20 to 60 years, mean 27) with deep carious lesions in permanent teeth (indirect or direct pulp capping,… · 12 months, Direct pulp capping
Pulp management for caries in adults: maintaining pulp vitality (2007) · Cochrane
Analysis 2.3 (clinical symptoms at 12 months following direct pulp capping, Life vs Dycal). Fitzgerald 1991: 151 teeth in 55 patients (analysis at tooth level, not patient level); substantial attrition (11 teeth lost…1 study · 151 participantsUngraded