What do systematic reviews say?

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

ACE Inhibitors showed no clear difference in death compared with calcium channel blockers (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 4.03 [0.45, 35.82]
  2 studies · 221 participants
  Low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

ACE Inhibitors showed no clear difference in graft loss compared with calcium channel blockers (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 7.37 [0.39, 140.35]
  1 study · 152 participants
  Low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 296 participants
  Moderate

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

It is very uncertain whether ACE Inhibitors changes acute rejection compared with calcium channel blockers (very low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 1.54 [1.14, 2.07]
  2 studies · 221 participants
  Very low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 142 participants
  Moderate

Calcium channel blockers vs placebo/no treatment

Calcium channel blockers may leads to lower graft loss compared with placebo/no treatment (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 0.75 [0.57, 0.99]
  17 studies · 1255 participants
  Low

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 332 participants
  Moderate

Angiotensin‐converting enzyme inhibitors vs calcium channel blockers

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 153 participants
  Moderate

Calcium channel blockers vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  18 studies · 1119 participants
  Moderate

Calcium channel blockers vs placebo/no treatment

Calcium channel blockers showed no clear difference in acute rejection compared with placebo/no treatment (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 1.02 [0.85, 1.23]
  11 studies · 771 participants
  Low

Calcium channel blockers vs placebo/no treatment

Calcium channel blockers showed no clear difference in withdrawal due to side effects compared with placebo/no treatment (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 0.99 [0.53, 1.87]
  2 studies · 156 participants
  Low

Calcium channel blockers vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 90 participants
  Low

Calcium channel blockers vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 590 participants
  Very low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

ACE inhibitors showed no clear difference in death compared with placebo/no treatment (low certainty).

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  RR 1 [0.07, 14.55]
  1 study · 30 participants
  Low

Angiotensin‐converting enzyme inhibitors vs placebo/no treatment

• Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 93 participants
  Low