What do systematic reviews say?

FAE vs placebo

FAE may leads to higher PASI 50 compared with placebo (low certainty).

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  RR 4.55 [2.8, 7.4]
  2 studies · 247 participants
  Low

FAE vs placebo

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 247 participants
  Low

FAE vs placebo

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

FAE vs MTX

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  Very low

FAE vs MTX

It is very uncertain whether FAE changes AEs leading to treatment discontinuation compared with MTX (very low certainty).

• Oral fumaric acid esters for psoriasis 2015 · Cochrane Headline outcomes only
  RR 0.19 [0.02, 1.53]
  1 study · 51 participants
  Very low

NB‐UVB vs topical PUVA

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs topical PUVA

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs topical PUVA

NB‐UVB showed no clear difference in clearance rate compared with topical PUVA (low certainty).

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  RR 0.09 [0.01, 1.56]
  1 study · 50 participants
  Low

NB‐UVB plus retinoid vs PUVA plus retinoid

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB plus retinoid vs PUVA plus retinoid

NB‐UVB plus retinoid showed no clear difference in percentage of participants reaching PASI 75 compared with PUVA plus retinoid (low certainty).

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  RR 0.89 [0.59, 1.35]
  1 study · 60 participants
  Low

NB‐UVB plus retinoid vs PUVA plus retinoid

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB plus retinoid vs PUVA plus retinoid

NB‐UVB plus retinoid showed no clear difference in clearance rate compared with PUVA plus retinoid (low certainty).

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  RR 0.93 [0.79, 1.1]
  2 studies · 90 participants
  Low

NB‐UVB vs selective BB‐UVB

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs selective BB‐UVB

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs selective BB‐UVB

NB‐UVB showed no clear difference in withdrawal due to side‐effects compared with selective BB‐UVB (low certainty).

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  RR 3 [0.32, 27.87]
  1 study · 100 participants
  Low

NB‐UVB vs selective BB‐UVB

NB‐UVB showed no clear difference in clearance rate compared with selective BB‐UVB (low certainty).

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  RR 1.4 [0.92, 2.13]
  1 study · 100 participants
  Low

NB‐UVB vs bath PUVA

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs bath PUVA

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs bath PUVA

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  no estimate extracted
  0 studies · 0 participants
  GRADE not reported

NB‐UVB vs bath PUVA

NB‐UVB showed no clear difference in clearance rate compared with bath PUVA (low certainty).

• Narrow‐band ultraviolet B phototherapy versus broad‐band ultraviolet B or psoralen‐ultraviolet A photochemotherapy for… 2013 · Cochrane Headline outcomes only
  RR 1.79 [0.46, 6.91]
  2 studies · 92 participants
  Low