Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

577 questions · 585 findings · 57 reviews

No studies found 61 · 10.4%GRADE not reported 46 · 7.9%Very low 206 · 35.2%Low 210 · 35.9%Moderate 52 · 8.9%High 10 · 1.7%

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Any sepsis – MOFS‐LE vs S‐LE – Pure F‐LE vs IL · parenterally fed preterm infants with cholestasis

It is very uncertain whether fish oil lipid emulsion (LE) changes any sepsis – MOFS‐LE vs S‐LE – Pure F‐LE vs IL compared with non‐fish oil LE (very low certainty).

1 finding from 1 review

Fish oil lipid emulsion (LE) vs non‐fish oil LE

ROP ≥ stage 3 or requiring surgery – all fish oil LE vs non‐fish oil LE · Parenterally fed preterm infants

It is very uncertain whether fish oil lipid emulsion (LE) changes ROP ≥ stage 3 or requiring surgery – all fish oil LE vs non‐fish oil… compared with non‐fish oil LE (very low certainty).

1 finding from 1 review

Fish oil lipid emulsion (LE) vs non‐fish oil LE

PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) – pure F‐LE vs S‐LE · parenterally fed term and late preterm infants with surgical conditions

It is very uncertain whether fish oil LE changes PNALD/cholestasis (conjugated bilirubin ≥ 2 mg/dL) Pure F‐LE vs S‐LE compared with non‐fish oil LE (very low certainty).

1 finding from 1 review

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Resolution of PNALD/cholestasis (conjugated bilirubin less than2 mg/dL) Pure F‐LE vs S‐LE · parenterally fed term and late preterm infants

It is very uncertain whether fish oil LE changes resolution of PNALD/cholestasis (conjugated bilirubin less than2… compared with non‐fish oil LE (very low certainty).

1 finding from 1 review

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Any sepsis (clinical and/or culture positive) · parenterally fed term and late preterm infants

It is very uncertain whether fish oil LE changes any sepsis (clinical or culture positive (or both)) MOFS‐LE vs S‐LE… compared with non‐fish oil LE (very low certainty).

1 finding from 1 review