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What do systematic reviews say?

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Evidence found and GRADE certainty

695 questions · 728 findings · 63 reviews · Headline outcomes only

No studies found 219 · 30.1%GRADE not reported 55 · 7.6%Very low 194 · 26.6%Low 136 · 18.7%Moderate 90 · 12.4%High 34 · 4.7%

Intralesional pentoxifylline vs daily simple dressing

Ulcer healing · ulceration and other skin changes caused by nerve damage in leprosy

It is very uncertain whether intralesional pentoxifylline changes primary outcome: healing of ulcer (complete healing of ulcer at 4… compared with daily simple dressing (very low certainty).

2 findings from 1 review