HIV Transmission or Death at 9 months among those whose HIV diagnostic testing was negative within 48 hours of birth · Breastfeeding infants of HIV‐infected mothers
An extended NVP regimen administered to infants for 14 weeks leads to lower HIV Transmission or Death at 9 months among those whose HIV… compared with sdNVP plus ZDV (1week) (high certainty).
1 finding from 1 review
HIV Transmission at 12 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers
An extended NVP regimen administered to infants for 6 weeks showed no clear difference in HIV Transmission at 12 months among those whose HIV diagnostic… compared with sdNVP (moderate certainty).
1 finding from 1 review
Infant Mortality at 12 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers
An extended NVP regimen administered to infants for 6 weeks probably leads to lower infant Mortality at 12 months among those whose HIV diagnostic… compared with sdNVP (moderate certainty).
1 finding from 1 review
HIV Transmission or Death at 12 months among those whose HIV diagnostic testing was negative within 7 days of birth · Breastfeeding infants of HIV‐infected mothers
An extended NVP regimen administered to infants for 6 weeks showed no clear difference in HIV Transmission or Death at 12 months among those whose HIV… compared with sdNVP (moderate certainty).
1 finding from 1 review
Intervention not reported
HIV Transmission at 7 months among those whose HIV diagnostic testing was negative at one month after birth · breastfeeding infants of HIV‐infected mothers
It is very uncertain whether the intervention changes HIV Transmission at 7 months among those whose HIV diagnostic… (very low certainty).
1 finding from 1 review
Intervention not reported
Infant Mortality at 18 months · breastfeeding infants of HIV‐infected mothers
It is very uncertain whether the intervention changes infant Mortality at 18 months (very low certainty).
1 finding from 1 review
Intervention not reported
HIV Transmission or Death at 18 months among those whose HIV diagnostic testing was negative at one month after birth · breastfeeding infants of HIV‐infected mothers
It is very uncertain whether the intervention changes HIV Transmission or Death at 18 months among those whose HIV… (very low certainty).
1 finding from 1 review
Intervention not reported
Infants with Grade 3/4 Signs or Symptoms · breastfeeding infants of HIV‐infected mothers
It is very uncertain whether the intervention changes infants with Grade 3/4 Signs or Symptoms (very low certainty).
1 finding from 1 review
Intervention not reported
Infants with Grade 3/4 Laboratory Abnormalities · breastfeeding infants of HIV‐infected mothers
It is very uncertain whether the intervention changes infants with Grade 3/4 Laboratory Abnormalities (very low certainty).
1 finding from 1 review
HIV Transmission at 24 months among those uninfected at birth · Breastfeeding infants of HIV‐infected mothers
An extended NVP regimen administered to infants for 14 weeks probably leads to lower HIV Transmission at 24 months among those uninfected at birth11 compared with sdNVP plus ZDV (1week) (moderate certainty).
1 finding from 1 review
Intervention not reported
Infant with Toxicity Events leading to cessation of ZDV · breastfeeding infants of HIV‐infected mothers
It is very uncertain whether the intervention changes infant with Toxicity Events leading to cessation of ZDV (very low certainty).
1 finding from 1 review
HIV transmission at 6 months among those whose HIV diagnostic testing was negative within 96 hours of birth · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in HIV transmission at 6 months among those whose HIV diagnostic… compared with an extended ZDV/3TC/ABC administered to mothers (low certainty).
1 finding from 1 review
Infant Mortality at 6 Months · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in infant Mortality at 6 months compared with an extended ZDV/3TC/ABC administered to mothers (low certainty).
1 finding from 1 review
HIV Transmission or Death at 6 months among those whose HIV diagnostic testing was negative within 96 hours of birth · HIV‐infected mothers and their breastfeeding infants
It is very uncertain whether an extended ZDV/3TC/LPV/r regimen administered to mothers changes HIV Transmission or Death at 6 months among those whose HIV… compared with an extended ZDV/3TC/ABC administered to mothers (very low certainty).
1 finding from 1 review
Infant Grade 3/4 Severe Adverse Events · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in infants with Grade 3/4 Severe Adverse Events compared with an extended ZDV/3TC/ABC administered to mothers (low certainty).
1 finding from 1 review
Maternal mortality ‐ not reported · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in maternal Mortality at 6 months compared with an extended ZDV/3TC/ABC administered to mothers (low certainty).
1 finding from 1 review
Maternal Grade 3/4 Severe Adverse Events · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in mothers with any Grade 3/4 Severe Adverse Event compared with an extended ZDV/3TC/ABC administered to mothers (low certainty).
1 finding from 1 review
Mothers with Severe Adverse Events Requiring Treatment Modification · HIV‐infected mothers and their breastfeeding infants
It is very uncertain whether an extended ZDV/3TC/LPV/r regimen administered to mothers changes mothers with Severe Adverse Events Requiring Treatment Modification compared with an extended ZDV/3TC/ABC administered to mothers (very low certainty).
1 finding from 1 review
HIV transmission at 6 months among those whose diagnostic testing was negative at 6 weeks after birth · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in HIV transmission at 6 months among those whose diagnostic testing… compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).
1 finding from 1 review
HIV transmission at 12 months among those whose diagnostic testing was negative at 6 weeks after birth · HIV‐infected mothers and their breastfeeding infants
An extended ZDV/3TC/LPV/r regimen administered to mothers may leads to lower HIV transmission at 12 months among those whose diagnostic testing… compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).
1 finding from 1 review