Findings

What do systematic reviews say?

4,667 questions · 21,760 findings · 2,177 reviews

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No studies found 4,173 · 19.2%GRADE not reported 2,300 · 10.6%Very low 5,276 · 24.2%Low 5,764 · 26.5%Moderate 3,298 · 15.2%High 949 · 4.4%

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Intervention not reported

Intra‐abdominal fluid collection, abscess · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…

The intervention showed no clear difference in intra‐abdominal fluid collection, abscess (low certainty).

1 finding from 1 review

Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy 2022 · Cochrane Headline outcomes only
OR 1.11 [0.71, 1.74]
7 studies · 788 participants
Low

Intervention not reported

Reoperations · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…

The intervention showed no clear difference in reoperations (low certainty).

1 finding from 1 review

Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy 2022 · Cochrane Headline outcomes only
OR 0.68 [0.34, 1.36]
5 studies · 682 participants
Low

Intervention not reported

Length of postoperative hospital stay (days) · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…

The intervention showed no clear difference in length of postoperative hospital stay (days) (low certainty).

1 finding from 1 review

Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy 2022 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 818 participants
Low

Intervention not reported

Quality of life (EQ‐5D, EORTC QLQ‐C30 and PAN26, GIQLI at 2, 4 and 12 weeks after surgery) · adults with any pancreatic diagnosis leading to an indication for elective (classical, pylorus‐preserving, pylorus‐resecting) partial…

1 finding from 1 review

Antecolic versus retrocolic reconstruction after partial pancreaticoduodenectomy 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 73 participants
Very low

Intervention not reported

Specimen · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

The review found no eligible studies for this question.

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Sputum · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 127 participants
High

Intervention not reported

Gastric aspirate · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 120 participants
Moderate

Intervention not reported

Stool · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 200 participants
Moderate

Intervention not reported

Nasopharyngeal aspirate · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 46 participants
Very low

Intervention not reported

Specimen · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

The review found no eligible studies for this question.

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

All specimens · children with presumed pulmonary tuberculosis Index tests: Xpert Ultra Role: an initial test Threshold for index tests: an automated…

1 finding from 1 review

Xpert MTB/RIF Ultra assay for tuberculosis disease and rifampicin resistance in children 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 3 participants
Very low

Intervention not reported

Test result · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

The review found no eligible studies for this question.

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

True positivespeople with pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 799 participants
Very low

Intervention not reported

False negativespeople incorrectly classified as not having pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 799 participants
Very low

Intervention not reported

True negativespeople without pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 429 participants
Very low

Intervention not reported

False positivespeople incorrectly classified as having pulmonary tuberculosis · people with presumptive pulmonary tuberculosisRole: an initial testIndex test: Xpert MTB/XDRThreshold for index test: an automated result…

1 finding from 1 review

Xpert MTB/XDR for detection of pulmonary tuberculosis and resistance to isoniazid, fluoroquinolones, ethionamide, and… 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 429 participants
Very low

Autologous platelet‐rich plasma vs placebo or no treatment

Adverse events · Adults (>18 years) having permanent tooth extraction (predominantly mandibular third molars)

1 finding from 1 review

Local interventions for the management of alveolar osteitis (dry socket) 2022 · Cochrane All outcomes
Follow-up: median 7 days
No adverse events were reported in these two trials.
2 studies
GRADE not reported

Visual or visual-tactile classification systems (any system: ICDAS, ERK, Nyvad, Downer, Lussi, UniViSS, or unspecified) vs Reference standard (histology, excavation, radiographs/microCT, or tooth separation)

Specificity for detection of enamel caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

6 findings from 1 review

Visual or visual‐tactile examination to detect and inform the diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies) · Non-histology reference standard (excavation, radiographs, separation)
Specificity 0.86 [0.76, 0.92]
Studies not reported
GRADE not reported
Visual or visual‐tactile examination to detect and inform the diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies) · High prevalence of dentine caries (>= 35%)
Specificity 0.75 [0.66, 0.82]
Studies not reported
GRADE not reported
Visual or visual‐tactile examination to detect and inform the diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies) · Histology reference standard
Specificity 0.76 [0.69, 0.81]
Studies not reported
GRADE not reported

Show 3 more findings

Visual or visual‐tactile examination to detect and inform the diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies)
Specificity 0.77 [0.72, 0.82]
67 studies
Low
Visual or visual‐tactile examination to detect and inform the diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies) · Occlusal surface
Specificity 0.74 [0.66, 0.81]
Studies not reported
GRADE not reported
Visual or visual‐tactile examination to detect and inform the diagnosis of enamel caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies) · Primary/mixed dentition
Specificity 0.79 [0.70, 0.85]
Studies not reported
GRADE not reported

Analogue (conventional) radiographs vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity for detection and diagnosis of early (enamel) caries · Asymptomatic children, adolescents, or adults presenting for clinical examination (in vivo studies), or extracted teeth of children or…

1 finding from 1 review

Imaging modalities to inform the detection and diagnosis of early caries 2021 · Cochrane All outcomes
Up to 3 months between index test and reference standard (in vivo studies)
Sensitivity 0.44 [0.38, 0.50]
51 studies
GRADE not reported

Lacebacks with fixed appliances vs Fixed appliances

Size of the lower jaw (arch length) · Children or adolescents (aged 16 years old or under) receiving orthodontic treatment to prevent or correct crowded teeth

Lacebacks with fixed appliances showed no clear difference in size of the lower jaw (arch length) compared with fixed appliances only (control); GRADE not reported.

1 finding from 1 review

Orthodontic treatment for crowded teeth in children 2021 · Cochrane All outcomes
6 months
MD 0.83 [-6.41, 8.07]
1 study · 62 participants
GRADE not reported