Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,815 questions · 6,211 findings · 638 reviews · Headline outcomes only

No studies found 1,052 · 16.9%GRADE not reported 441 · 7.1%Very low 1,700 · 27.4%Low 1,651 · 26.6%Moderate 1,070 · 17.2%High 297 · 4.8%

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Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)

Proportion of wounds healed · pilonidal sinus

Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in proportion of wounds healed compared with off‐midline closure (Limberg flap) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)

Recurrence · pilonidal sinus

Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in recurrence rate compared with off‐midline closure (Limberg flap) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)

Wound infection · pilonidal sinus

Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in wound infection compared with off‐midline closure (Limberg flap) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure (Karydakis flap) vs off‐midline closure (Limberg flap)

Wound dehiscence · pilonidal sinus

Summary of findings table ‐ Off‐midline closure (Karydakis flap) showed no clear difference in wound dehiscence compared with off‐midline closure (Limberg flap) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Off‐midline closure vs conventional midline closure

Proportion of wounds healed · pilonidal sinus

It is very uncertain whether summary of findings table ‐ Off‐midline closure changes proportion of wounds healed compared with conventional midline closure (very low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs vaginal prostaglandin E2

Vaginal delivery not achieved within 24 hours · third trimester induction of labour in women with a viable fetus

Balloon (Foley or ATAD) showed no clear difference in vaginal delivery not achieved in 24 hours compared with vaginal prostaglandin E2 (low certainty).

1 finding from 1 review

Balloon (Foley or ATAD) vs low‐dose vaginal misoprostol

Serious neonatal morbidity or perinatal death · third trimester induction of labour in women with a viable fetus

It is very uncertain whether balloon (Foley or ATAD) changes serious neonatal morbidity or perinatal death compared with low‐dose vaginal misoprostol (very low certainty).

1 finding from 1 review