Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,410 questions · 8,901 findings · 1,091 reviews

No studies found 1,687 · 19%GRADE not reported 1,469 · 16.5%Very low 1,969 · 22.1%Low 2,060 · 23.1%Moderate 1,302 · 14.6%High 414 · 4.7%

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Surface‐modified vs standard catheter

Death from any cause at day 28 of · AKI patients receiving CKRT

It is very uncertain whether surface‐modified changes death from any cause at day 28 of compared with standard double‐lumen catheter with identical geometry and flow design (very low certainty).

1 finding from 1 review

Surface‐modified vs standard catheter

Recovery of kidney function · AKI patients receiving CKRT

Surface‐modified showed no clear difference in recovery of kidney function compared with standard double‐lumen catheter with identical geometry and flow design (low certainty).

1 finding from 1 review

Surface‐modified vs standard catheter

Vascular access complications · AKI patients receiving CKRT

Surface‐modified showed no clear difference in vascular access complications compared with standard double‐lumen catheter with identical geometry and flow design (low certainty).

1 finding from 1 review

Higher threshold (500 mL per six hours or greater) vs lower threshold (less than 500 mL per six hours) at time of aspiration

Mortality (at the end of · adults receiving EN via nasogastric or gastrostomy tube

It is very uncertain whether higher threshold (500 mL per six hours or greater) changes mortality (at the end of compared with lower threshold (less than 500 mL per six hours) at time of aspiration (very low certainty).

1 finding from 1 review