Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,973 questions · 3,072 findings · 410 reviews · Headline outcomes only

No studies found 559 · 18.2%GRADE not reported 143 · 4.7%Very low 654 · 21.3%Low 833 · 27.1%Moderate 683 · 22.2%High 200 · 6.5%

Intervention not reported

Antibiotic prescriptions (number of courses/person/year) **Corticosteroids not meta‐analysed · adults (> 18 years of age) with either COPD or recurrent acute exacerbations of chronic bronchitis

The intervention may leads to higher antibiotic prescriptions (number of courses/person/year)… (low certainty).

1 finding from 1 review

Intervention not reported

Adverse events (number of adverse events/person/year) · adults (> 18 years of age) with either COPD or recurrent acute exacerbations of chronic bronchitis

The intervention showed no clear difference in adverse events (number of adverse events/person/year) (low certainty).

1 finding from 1 review

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Survival to hospital discharge · Patients with non‐trauma related out‐of‐hospital cardiac arrest

Continuous chest compression alone leads to higher survival to hospital discharge compared with interrupted chest compression plus artificial ventilation (high certainty).

1 finding from 1 review

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Survival to hospital admission · Patients with non‐trauma related out‐of‐hospital cardiac arrest

Continuous chest compression alone showed no clear difference in survival to hospital admission compared with interrupted chest compression plus artificial ventilation (moderate certainty).

1 finding from 1 review

Continuous chest compression alone vs interrupted chest compression plus artificial ventilation

Neurological function at hospital discharge, measured by cerebral performance category (CPC) · Patients with non‐trauma related out‐of‐hospital cardiac arrest

Continuous chest compression alone showed no clear difference in neurological outcomes at hospital discharge Measured as 'good' or… compared with interrupted chest compression plus artificial ventilation (moderate certainty).

1 finding from 1 review