Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,703 questions · 15,007 findings · 1,416 reviews

No studies found 2,881 · 19.2%GRADE not reported 1,551 · 10.3%Very low 3,111 · 20.7%Low 3,881 · 25.9%Moderate 2,669 · 17.8%High 914 · 6.1%

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Summary of findings table ‐ Stem Cell vs placebo or control

CDAI <150 at 24 weeks · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes CDAI <150 at 24 weeks compared with placebo or Control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Fistula Closure short‐term · Induction of Remission in Medically Refractory Crohn's Disease

Summary of findings table ‐ Stem Cell may leads to higher fistula Closure short‐term compared with placebo or Control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Fistula closure in long‐term · Induction of Remission in Medically Refractory Crohn's Disease

Summary of findings table ‐ Stem Cell may leads to higher fistula closure in long‐term compared with placebo or Control (low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Total adverse events · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes total Adverse Events compared with placebo or Control (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Stem Cell vs placebo or control

Withdrawals due to adverse events · Induction of Remission in Medically Refractory Crohn's Disease

It is very uncertain whether summary of findings table ‐ Stem Cell changes withdrawal due to adverse events compared with placebo or Control (very low certainty).

1 finding from 1 review

Osmotic‐release oral system methylphenidate vs placebo

Proportion of individuals withdrawing from treatment · people with ADHD and epilepsy

Osmotic‐release oral system methylphenidate probably leads to higher proportion of people withdrawing from treatment compared with placebo (moderate certainty).

1 finding from 1 review