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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

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No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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4% articaine, 1:100,000 epinephrine vs 2% lidocaine, 1:100,000 epinephrine

Adverse effects: pain following injection · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

4% articaine, 1:100,000 epinephrine probably leads to higher adverse effects: pain following injection, Heft-Parker VAS 0-170 mm compared with 2% lidocaine, 1:100,000 epinephrine (moderate certainty).

1 finding from 1 review

Any surgical or non-surgical technique or material used for the treatment of post-extraction bleeding vs Placebo, no treatment, or another active antifungal intervention

Costs: direct cost of treatment · People of any age and either gender with post-extraction bleeding, regardless of type of teeth (anterior or posterior, mandibular or…

The review found no eligible studies for this question.

1 finding from 1 review

Single-stage alginate impression (simplified method) vs Two stage-two step zinc-oxide eugenol (ZoE) traditional method

Operator-assessed quality of the denture (retention and stability) · Completely edentulous people
1 finding from 1 review

Altered-cast impression technique (ACIP), polyether vs One-piece cast technique (OPC), polyether

Participant-reported quality of the denture (general satisfaction) · Partially edentulous people requiring a tooth- and tissue-supported (distal-extension) removable partial denture
1 finding from 1 review

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Success of local anaesthesia, absence of pain (clinical testing of healthy pulps, hard and soft tissues) · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…

It is very uncertain whether 4% articaine, 1:200,000 epinephrine changes success of local anaesthesia, absence of pain (clinical testing of… compared with 4% articaine, 1:100,000 epinephrine (very low certainty).

1 finding from 1 review

Ferric sulphate (FS) vs Buffered glutaraldehyde

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth
1 finding from 1 review
  • Pulp treatment for extensive decay in primary teeth 2018 · Cochrane All outcomes
    6 months
    Assessed pain, soft tissue, mobility, radiolucency, root resorption, pulp canal obliteration (Goyal 2016); no clinical/radiological failure outcome; no significant differences
    1 study · 60 participants
    GRADE not reported

Zinc oxide and eugenol (ZOE) vs RC Fill

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

Endoflas (CH + ZOE + iodoform) vs RC Fill

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

4% articaine, 1:200,000 epinephrine vs 4% articaine, 1:100,000 epinephrine

Adverse effects: allergy to local anaesthetic · Participants of any age and gender undergoing dental procedures, and volunteers who took part in simulated scenario studies in which…
1 finding from 1 review

FMA stepwise advancement (SWG) vs FMA single step advancement (SSG)

Final overjet · Adolescents (age 12 to 16 years) receiving orthodontic treatment to correct prominent upper front teeth (Class II malocclusion)

FMA stepwise advancement (SWG) showed no clear difference in final overjet compared with FMA single step advancement (SSG); GRADE not reported.

1 finding from 1 review

Mineral trioxide aggregate (MTA) vs IRM (intermediate restorative material)

Outcome not reported · Children with extensive decay involving the dental pulp in primary teeth

The review found no eligible studies for this question.

1 finding from 1 review

6% HP strip vs placebo

Tooth whitening - assessed by the dentist · Adults (>=18 years) undergoing home-based bleaching (including tetracycline- and smoking-stained teeth, any baseline shade)

It is very uncertain whether 6% HP strip changes tooth whitening - assessed by the dentist compared with placebo (very low certainty).

1 finding from 1 review