Findings

What do systematic reviews say?

2,908 questions · 3,101 findings · 509 reviews

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No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Intervention not reported

Decrease in alcohol intake (g) · alcohol consumers with high blood pressure

1 finding from 1 review

Alcohol intake reduction for controlling hypertension 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 269 participants
Low

Intervention not reported

Proportion of subjects with SBP < 140 mmHg and DBP < 90 mmHg · alcohol consumers with high blood pressure

It is very uncertain whether the intervention changes proportion of subjects with SBP < 140 mmHg and DBP < 90 mmHg (very low certainty).

1 finding from 1 review

Alcohol intake reduction for controlling hypertension 2020 · Cochrane Headline outcomes only
RR 1.21 [0.88, 1.65]
1 study · 269 participants
Very low

Supine midline head position vs any other supine head position

Intraventricular haemorrhage · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes intraventricular haemorrhage, any grade compared with any other supine head position (very low certainty).

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
RR 1.11 [0.78, 1.56]
3 studies · 290 participants
Very low

Supine midline head position vs any other supine head position

Intraventricular haemorrhage, Papile grade 3/4 · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes intraventricular haemorrhage, grade 3 to 4 compared with any other supine head position (very low certainty).

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
RR 0.71 [0.37, 1.33]
3 studies · 290 participants
Very low

Supine midline head position vs any other supine head position

All‐cause mortality during hospital stay · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes mortality during initial hospitalisation compared with any other supine head position (very low certainty).

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
RR 0.5 [0.28, 0.9]
3 studies · 290 participants
Very low

Supine midline head position vs any other supine head position

Retinopathy of prematurity, > stage 3 · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

It is very uncertain whether supine midline head position changes retinopathy of prematurity, > stage 3 compared with any other supine head position (very low certainty).

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
RR 0.9 [0.41, 1.97]
2 studies · 222 participants
Very low

Supine midline head position vs any other supine head position

Long‐term neurodevelopmental outcome ‒not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Supine midline head position vs any other supine head position

Major neurodevelopmental disability ‒not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Supine midline head position vs any other supine head position

Cerebellar haemorrhage on brain ultrasound ‐ not reported · very preterm infants with or at risk of germinal matrix‐intraventricular haemorrhage in preterm infants

The review found no eligible studies for this question.

1 finding from 1 review

Head midline position for preventing the occurrence or extension of germinal matrix‐intraventricular haemorrhage in… 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs placebo

Length of delirium episode · end‐of‐life patients with advanced cancer and an episode of agitated delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs chlorpromazine

Mortality from all causes · adult AIDS patients with delirium

It is very uncertain whether benzodiazepines (lorazepam) changes mortality from all causes compared with antipsychotics (chlorpromazine) (very low certainty).

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
RR 0.87 [0.23, 3.26]
1 study · 19 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Length of delirium episode · adult AIDS patients with delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs haloperidol

Severity of delirium · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Any adverse event ESRS, higher = worse · adult AIDS patients with delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs haloperidol

Duration of hospital admission (days) · adult AIDS patients with delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs haloperidol

Mortality from all causes · adult AIDS patients with delirium

It is very uncertain whether benzodiazepines (lorazepam) changes mortality from all causes compared with antipsychotics (haloperidol) (very low certainty).

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
RR 1.83 [0.34, 9.92]
1 study · 17 participants
Very low

Benzodiazepines (lorazepam) vs placebo

Severity of delirium · end‐of‐life patients with advanced cancer and an episode of agitated delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Low

Benzodiazepines (lorazepam) vs placebo

Any adverse event · end‐of‐life patients with advanced cancer and an episode of agitated delirium

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Benzodiazepines (lorazepam) vs placebo

Length of hospital stay · end‐of‐life patients with advanced cancer and an episode of agitated delirium

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 58 participants
Low

Benzodiazepines (lorazepam) vs placebo

Mortality from all causes · end‐of‐life patients with advanced cancer and an episode of agitated delirium

Benzodiazepines (lorazepam) showed no clear difference in mortality from all causes compared with placebo (low certainty).

1 finding from 1 review

Benzodiazepines for treatment of patients with delirium excluding those who are cared for in an intensive care unit 2020 · Cochrane Headline outcomes only
RR 0.33 [0.04, 3.02]
1 study · 58 participants
Low