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Evidence found and GRADE certainty

4,756 questions · 11,779 findings · 747 reviews · Headline outcomes only

No studies found 3,205 · 27.2%GRADE not reported 628 · 5.3%Very low 3,261 · 27.7%Low 2,913 · 24.7%Moderate 1,453 · 12.3%High 319 · 2.7%

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Mycophenolate sodium + oral steroids vs oral steroids alone

Complete remission · minimal change disease in adults with nephrotic syndrome

Mycophenolate sodium + oral steroids showed no clear difference in complete remission Time frame: 4 weeks compared with oral steroids alone (moderate certainty).

2 findings from 1 review

Mycophenolate sodium + oral steroids vs oral steroids alone

Complete or partial remission · minimal change disease in adults with nephrotic syndrome

Mycophenolate sodium + oral steroids showed no clear difference in complete or partial remission Time frame: 24 weeks to end of treatment compared with oral steroids alone (moderate certainty).

1 finding from 1 review

Mycophenolate sodium + oral steroids vs oral steroids alone

Adverse events: new‐onset glucose intolerance · minimal change disease in adults with nephrotic syndrome

Mycophenolate sodium + oral steroids showed no clear difference in adverse events: new‐onset glucose intolerance compared with oral steroids alone (low certainty).

1 finding from 1 review

Intervention not reported

Mobilityd ‐ overall analysis Using different mobility scales: MILA (range 0 to 36), EMS (range 0 to 20), BBS (range 0 to 56), PPME (range 0 to 12), Koval (range 1 to 7). Higher values indicate better mobility (except MILA and Koval, where scale wa... · adults following hip fracture surgery

The intervention may leads to higher mobilityd ‐ overall analysis Using different mobility scales: MILA… (low certainty).

1 finding from 1 review

Intervention not reported

Mobility scales, using EMS (range 0 to 20). Higher values indicate better mobility · adults following hip fracture surgery

The intervention showed no clear difference in mobility scales, using EMS (range 0 to 20). Higher values indicate… (low certainty).

1 finding from 1 review

Intervention not reported

TUG (lower score = faster) · adults following hip fracture surgery

The intervention showed no clear difference in TUG (lower score = faster) (low certainty).

1 finding from 1 review

Intervention not reported

Mobilityd ‐ overall analysis Using different mobility scales: mPPT (range 0 to 36), POMA (range 0 to 30), SPPB (range 0 to 12), PPME (range 0 to 12). A higher score indicates better mobility. · adults following hip fracture surgery

The intervention leads to higher mobilityd ‐ overall analysis Using different mobility scales: mPPT… (high certainty).

1 finding from 1 review

Intervention not reported

Walking speedg ‐ overall analysis Measured using metres/second (m/s) and metres/minute (m/min). A higher score indicates faster walking. · adults following hip fracture surgery

The intervention leads to higher walking speedg ‐ overall analysis Measured using metres/second (m/s)… (high certainty).

1 finding from 1 review

Intervention not reported

Functioningi ‐ overall analysis Using different functioning scales: FSQ (range 0 to 36), BI (range 0 to 100), AM‐PAC daily activity (range 9 to 101), COPM (range 0 to 20), LEFS (range 0 to 80), NEADL (range 0 to 66). A higher score indicates bette... · adults following hip fracture surgery

The intervention leads to higher functioningi ‐ overall analysis Using different functioning scales:… (high certainty).

1 finding from 1 review

Intervention not reported

HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12 (range 0 to 100), and WHOQOL‐BREF (range 0 to 130). A higher score indicates better quality of life. · adults following hip fracture surgery

The intervention showed no clear difference in HRQoL using EQ‐ 5D (range 0 to 1), SF‐36 (range 0 to 100), SF‐12… (moderate certainty).

1 finding from 1 review