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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Population

Intervention or exposure

Comparison

Outcome

Any field or review title

Field or topic

Source

Review versions

1,105 questions in 84 reviews · Metabolic and Endocrine Disorders

current versions

No studies 434 · 39.3%Ungraded 32 · 2.9%Very low 246 · 22.3%Low 237 · 21.4%Moderate 132 · 11.9%High 24 · 2.2%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Question	Effect	Evidence	Status / GRADE
Intervention NR Morbidity · children (aged 6 to 11 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from… (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Socioeconomic effects · children (aged 6 to 11 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from… (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR a) Change in BMI · adolescents (aged 12‐17 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents… (2017) · Cochrane	no estimate extracted	28 studies · 2774 participants	Moderate
Intervention NR Adverse events · adolescents (aged 12‐17 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents… (2017) · Cochrane	no estimate extracted	NR	Low
Intervention NR Health‐related quality of life Validated self‐reported measures · adolescents (aged 12‐17 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents… (2017) · Cochrane	no estimate extracted	7 studies · 972 participants	Low
Intervention NR All‐cause mortality · adolescents (aged 12‐17 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents… (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Morbidity · adolescents (aged 12‐17 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents… (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Socioeconomic effects · adolescents (aged 12‐17 years) being overweight or obese Diet, physical activity and behavioural interventions for the treatment of overweight or obese adolescents… (2017) · Cochrane	no estimate extracted	NR	No studies
Intervention NR All‐cause mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related morbidity Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Health‐related quality of life Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Patient satisfaction Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Adverse events: a. mild hypoglycaemia (episodes per participant) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	8 studies · 590 participants	Low
Intervention NR HbA1c, change from baseline (%) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	9 studies · 698 participants	Low
Intervention NR All‐cause mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related morbidity Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Health‐related quality of life Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Patient satisfaction Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Adverse events: a. mild to moderate hypoglycaemia (episodes per participant) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	2 studies · 760 participants	Low
Intervention NR HbA1c, change from baseline (%) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	3 studies · 785 participants	Low
Intervention NR All‐cause mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related morbidity Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Health‐related quality of life Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Patient satisfaction Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Adverse events: a. mild hypoglycaemia (% of participants) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	4 studies · 583 participants	Low
Intervention NR HbA1c, change from baseline (%) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	3 studies · 448 participants	Low
Intervention NR All‐cause mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related morbidity Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related morbidity Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Health‐related quality of life Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Patient satisfaction Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Adverse events: a. hypoglycaemia (% of participants) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	3 studies · 503 participants	Low
Intervention NR HbA1c, change from baseline (%) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	2 studies · 265 participants	Low
Intervention NR Health‐related quality of life Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Patient satisfaction Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Adverse events: a. mild hypoglycaemia (episodes per participant) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	8 studies · 239 participants	Low
Intervention NR HbA1c, change from baseline (%) Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	9 studies · 316 participants	Low
Intervention NR All‐cause mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Intervention NR Diabetes‐related mortality Insulin monotherapy compared with the addition of oral glucose‐lowering agents to insulin for people with… (2016) · Cochrane	no estimate extracted	NR	No studies
Supportive interventions for enhancing dietary intake vs comparators All‐cause mortality · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	RR 0.78 [0.66, 0.92]	12 studies · 6683 participants	Moderate
Supportive interventions for enhancing dietary intake vs comparators Morbidity/complications (number of participants with any medical complication) · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	no estimate extracted	5 studies · 4015 participants	Very low
Supportive interventions for enhancing dietary intake vs comparators Health‐related quality of life and patient satisfaction · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	no estimate extracted	5 studies · 4451 participants	Low
Supportive interventions for enhancing dietary intake vs comparators Hospitalisation and institutionalisation (days) · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	no estimate extracted	5 studies · 667 participants	Very low
Supportive interventions for enhancing dietary intake vs comparators Adverse events · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	no estimate extracted	3 studies · 4108 participants	Very low
Supportive interventions for enhancing dietary intake vs comparators Nutritional status (weight change in kg) · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	no estimate extracted	17 studies · 2024 participants	Moderate
Supportive interventions for enhancing dietary intake vs comparators Economic costs · malnourished or nutritionally at‐risk adults Supportive interventions for enhancing dietary intake in malnourished or nutritionally at‐risk adults (2016) · Cochrane	no estimate extracted	3 studies · 1152 participants	Very low