Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

759 questions in 57 reviews · Colorectal

current versions
No studies 91 · 12%Ungraded 12 · 1.6%Very low 209 · 27.5%Low 229 · 30.2%Moderate 160 · 21.1%High 58 · 7.6%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Glue vs suture
Duration of operation (mins) · patients with recurrence and pain in Lichtenstein inguinal hernioplasty
Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty (2017) · Cochrane
no estimate extracted9 studies · 1790 participantsLow
Glue vs suture
Wound/superficial infection · patients with recurrence and pain in Lichtenstein inguinal hernioplasty
Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty (2017) · Cochrane
OR 1.23 [0.37, 4.11]7 studies · 818 participantsLow
Glue vs suture
Mesh/deep infection · patients with recurrence and pain in Lichtenstein inguinal hernioplasty
Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty (2017) · Cochrane
OR 0.67 [0.16, 2.83]8 studies · 1448 participantsLow
Glue vs suture
Haematoma · patients with recurrence and pain in Lichtenstein inguinal hernioplasty
Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty (2017) · Cochrane
OR 0.52 [0.31, 0.86]10 studies · 1439 participantsModerate
Glue vs suture
Recovery time to daily activities (days) · patients with recurrence and pain in Lichtenstein inguinal hernioplasty
Mesh fixation with glue versus suture for chronic pain and recurrence in Lichtenstein inguinal hernioplasty (2017) · Cochrane
no estimate extracted3 studies · 403 participantsLow
Chromoscopy vs conventional colonoscopy
Total polyps (neoplastic and non‐neoplastic) detected · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
MD 0.89 [0.74, 1.04]7 studies · 2727 participantsLow
Chromoscopy vs conventional colonoscopy
Total neoplastic lesions · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
MD 0.33 [0.25, 0.41]7 studies · 2727 participantsLow
Chromoscopy vs conventional colonoscopy
Number of participants with at least 1 polyp (neoplastic or non‐neoplastic) · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
OR 1.87 [1.51, 2.3]4 studies · 1515 participantsLow
Chromoscopy vs conventional colonoscopy
Total participants with at least 1 neoplastic lesion · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
OR 1.53 [1.31, 1.79]7 studies · 2727 participantsLow
Chromoscopy vs conventional colonoscopy
Number of diminutive neoplastic lesions · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
MD 0.21 [0.1, 0.32]4 studies · 1409 participantsLow
Chromoscopy vs conventional colonoscopy
Participants with diminutive neoplastic lesions · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
OR 1.51 [1.19, 1.92]4 studies · 1757 participantsLow
Chromoscopy vs conventional colonoscopy
Number of participants with 3 or more adenomas (in studies with single intubation) · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
OR 4.63 [1.99, 10.8]2 studies · 519 participantsLow
Chromoscopy vs conventional colonoscopy
Adverse events · people undergoing colonoscopy for the detection of polyps
Chromoscopy versus conventional endoscopy for the detection of polyps in the colon and rectum (2016) · Cochrane
no estimate extractedNRNo studies
Intervention NR
Change in core temperature (ºC) · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted19 studies · 1100 participantsLow
Intervention NR
Day 1 pain score (0 to 10‐point VAS) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted14 studies · 991 participantsLow
Intervention NR
Day 1 pain score: heated, humidified vs cold (abdominal) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted10 studies · 670 participantsLow
Intervention NR
Day 1 pain score: heated, humidified vs cold (shoulder) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted3 studies · 171 participantsVery low
Intervention NR
Day 1 pain score: heated only vs cold · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted3 studies · 150 participantsModerate
Intervention NR
Day 2 pain score · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted10 studies · 695 participantsLow
Intervention NR
Day 2 pain score: heated, humidified vs cold (abdominal) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 442 participantsLow
Intervention NR
Day 2 pain score: heated, humidified vs cold (shoulder) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted2 studies · 111 participantsVery low
Intervention NR
Day 2 pain score: heated only vs cold · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted3 studies · 142 participantsLow
Intervention NR
Day 1 pain score for low risk of bias studies · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 570 participantsHigh
Intervention NR
Day 1 pain score for low risk of bias studies: heated, humidified vs cold (abdominal) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 460 participantsHigh
Intervention NR
Change in core temperature: heated, humidified vs cold · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted14 studies · 885 participantsLow
Intervention NR
Day 1 pain score for low risk of bias studies: heated, humidified vs cold (shoulder) · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted2 studies · 110 participantsModerate
Intervention NR
Day 2 pain score for low risk of bias studies · Laparoscopic abdominal surgery (pain score)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted5 studies · 380 participantsHigh
Intervention NR
Up to 6 h · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted4 studies · 231 participantsModerate
Intervention NR
Day 1 morphine · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted9 studies · 573 participantsModerate
Intervention NR
Day 1 morphine: heated, humidified vs cold · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 481 participantsLow
Intervention NR
Day 1 morphine: heated only vs cold · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted3 studies · 92 participantsLow
Intervention NR
Day 2 morphine · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 532 participantsModerate
Intervention NR
Day 2 morphine: heated, humidified vs cold · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted6 studies · 410 participantsModerate
Intervention NR
Day 2 morphine: heated only vs cold · Laparoscopic abdominal surgery (morphine consumption)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted2 studies · 122 participantsLow
Intervention NR
Hospital stay (days) · Laparoscopic abdominal surgery (hospital stay)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted10 studies · 685 participantsModerate
Intervention NR
Change in core temperature: heated only vs cold · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 215 participantsLow
Intervention NR
Hospital stay: heated, humidified vs cold · Laparoscopic abdominal surgery (hospital stay)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted9 studies · 563 participantsModerate
Intervention NR
Hospital stay: heated only vs cold · Laparoscopic abdominal surgery (hospital stay)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted2 studies · 122 participantsModerate
Intervention NR
Risk of bias not clear · Laparoscopic abdominal surgery (hospital stay)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted1 participantsUngraded
Intervention NR
Recovery time (minutes) · Laparoscopic abdominal surgery (recovery time)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted6 studies · 327 participantsLow
Intervention NR
Recovery time for low risk of bias studies · Laparoscopic abdominal surgery (recovery time)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted5 studies · 277 participantsModerate
Intervention NR
Times cleaned · Laparscopic abdominal surgery (lens fogging)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 341 participantsLow
Intervention NR
Operative time (minutes) · Laparoscopic abdominal surgery (operative time)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted20 studies · 1318 participantsVery low
Intervention NR
Operative time: heated, humidified vs cold · Laparoscopic abdominal surgery (operative time)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted15 studies · 1033 participantsVery low
Intervention NR
Operative time: heated only vs cold · Laparoscopic abdominal surgery (operative time)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted7 studies · 285 participantsLow
Intervention NR
Change in core temperature for known low risk of bias studies · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted10 studies · 653 participantsModerate
Intervention NR
Change in core temperature for known low risk of bias studies: heated, humidified vs cold · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted8 studies · 561 participantsModerate
Intervention NR
Change in core temperature for low risk of bias studies: heated only vs cold · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted3 studies · 92 participantsModerate
Intervention NR
Change in core temperature with external warming · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted8 studies · 545 participantsModerate
Intervention NR
Change in core temperature without external warming · Laparoscopic abdominal surgery (core temperature)
Heated insufflation with or without humidification for laparoscopic abdominal surgery (2016) · Cochrane
no estimate extracted6 studies · 340 participantsModerate