Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

258 questions · 305 findings · 33 reviews

No studies found 66 · 21.6%GRADE not reported 45 · 14.8%Very low 85 · 27.9%Low 58 · 19%Moderate 37 · 12.1%High 14 · 4.6%

Topical thalidomide vs Another topical agent or placebo

Healing of ulceration · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Topical thalidomide vs Another topical agent or placebo

Duration to heal oral ulcerations after initiation of treatment · HIV‐infected adults (> 13 years of age, per CDC) with one or more painful intraoral aphthous ulcers

The review found no eligible studies for this question.

1 finding from 1 review
  • No studies were included in this review. A total of 233 abstracts were retrieved; 25 were selected as potentially eligible but all were excluded (10 reported systemic rather than topical treatment; 3 non‐RCTs; 6…
    0 studies
    No studies found

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Serious neonatal morbidity

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes serious neonatal morbidity (Reported in Miller 2014 as 'composite… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Perinatal loss: all ‐ including miscarriages and stillbirth (Note: data not available for neonatal death)

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes perinatal loss: all ‐ including miscarriages and stillbirth (Note:… compared with cervical cerclage alone (very low certainty).

1 finding from 1 review

Cervical cerclage in combination with antibiotics and tocolytics vs cervical cerclage

Preterm birth less than 34 weeks' gestation

It is very uncertain whether cervical cerclage in combination with antibiotics and tocolytics changes preterm birth < 34 completed weeks of pregnancy compared with cervical cerclage alone (very low certainty).

1 finding from 1 review