Cerebral palsy · women at risk of preterm birth
Dexamethasone showed no clear difference in cerebral palsy compared with betamethasone – child outcomes (low certainty).
1 finding from 1 review
Chorioamnionitis · women at risk of preterm birth
Dexamethasone showed no clear difference in chorioamnionitis compared with betamethasone – maternal outcomes (moderate certainty).
1 finding from 1 review
Maternal puerperal sepsis · women at risk of preterm birth
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Maternal adverse effects of therapy · women at risk of preterm birth
Dexamethasone showed no clear difference in maternal adverse effects of therapy compared with betamethasone – maternal outcomes (moderate certainty).
1 finding from 1 review
Any known death after randomisation (fetal, neonatal, child, child as adult) · women at risk of preterm birth
Dexamethasone showed no clear difference in any known death after randomisation (fetal, neonatal, child, child… compared with betamethasone – fetal/neonatal outcomes (moderate certainty).
1 finding from 1 review
Respiratory distress syndrome · women at risk of preterm birth
Dexamethasone showed no clear difference in respiratory distress syndrome compared with betamethasone – fetal/neonatal outcomes (high certainty).
1 finding from 1 review
Intraventricular haemorrhage · women at risk of preterm birth
Dexamethasone showed no clear difference in intraventricular haemorrhage compared with betamethasone – fetal/neonatal outcomes (low certainty).
1 finding from 1 review
Chronic lung disease · women at risk of preterm birth
Dexamethasone showed no clear difference in chronic lung disease compared with betamethasone – fetal/neonatal outcomes (moderate certainty).
1 finding from 1 review
Necrotising enterocolitis · women at risk of preterm birth
Dexamethasone showed no clear difference in necrotising enterocolitis compared with betamethasone – fetal/neonatal outcomes (low certainty).
1 finding from 1 review
Clinical pregnancy rate · women with polycystic ovary syndrome
It is very uncertain whether metformin changes clinical pregnancy rate per woman ‐ short protocol GnRH‐antagonist compared with placebo or no treatment (very low certainty).
Miscarriage · women with polycystic ovary syndrome
Metformin showed no clear difference in miscarriage rate per woman compared with placebo or no treatment (low certainty).
Live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32 kg/m2 · women with polycystic ovary syndrome
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).
Live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (very low certainty).
Gastrointestinal adverse events · women with polycystic ovary syndrome
The review found no eligible studies for this question.
no estimate extracted
Studies not reported
No studies found
no estimate extracted
Studies not reported
No studies found
Clinical pregnancy rate per woman Participants with BMI < 30 kg/m2 or ≤ 32 kg/m2a · women with polycystic ovary syndrome
Metformin may leads to higher clinical pregnancy rate per womanaParticipants with BMI < 30 kg/m2… compared with clomiphene citrate (low certainty).
Clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower clinical pregnancy rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Ovulation rate per woman fParticipants with BMI < 30 kg/m2 · women with polycystic ovary syndrome
Metformin showed no clear difference in ovulation rate per woman fParticipants with BMI < 30 kg/m2 compared with clomiphene citrate (low certainty).
Ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 · women with polycystic ovary syndrome
Metformin may leads to lower ovulation rate per woman fParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (low certainty).
Change in eGFR · preventing the progression of CKD
1 finding from 1 review
Serious adverse events ( · preventing the progression of CKD
Metformin showed no clear difference in serious adverse events ( compared with active control (moderate certainty).
1 finding from 1 review