Clinical improvement: discharged alive ( · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
Summary of findings table ‐ High‐dose dexamethasone (12 mg or higher) showed no clear difference in clinical improvement: discharged alive ( compared with low‐dose dexamethasone (6 mg to 8 mg) (low certainty).
1 finding from 1 review
Clinical worsening: need for invasive mechanical ventilation, or death at up to day 28 · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse events ( · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
1 finding from 1 review
Adverse events: all grades · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
1 finding from 1 review
Hospital‐acquired infections ( · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
1 finding from 1 review
Invasive fungal infection · hospitalised individuals with unknown vaccination status and a confirmed diagnosis of symptomatic COVID‐19
1 finding from 1 review
Live birth rate per woman · women undergoing assisted reproduction
Endometrial injury showed no clear difference in live birth per woman randomised (studies at low risk of selection… compared with control (moderate certainty).
3 findings from 1 review
OR 1.12 [0.98, 1.28]
8 studies · 4402 participants
Moderate
OR 1.13 [0.63, 2.03]
1 study · 229 participants
Low
no estimate extracted
29 studies · 7792 participants
Very low
Miscarriage per woman randomised (studies at low risk of selection bias and other bias) · women undergoing assisted reproduction
Endometrial injury showed no clear difference in miscarriage per woman randomised (studies at low risk of selection… compared with control (moderate certainty).
1 finding from 1 review
Miscarriage · women undergoing assisted reproduction
Endometrial injury showed no clear difference in miscarriage per woman randomised: sensitivity analysis (no high risk) compared with control (low certainty).
2 findings from 1 review
Clinical pregnancy · women undergoing assisted reproduction
Endometrial injury showed no clear difference in clinical pregnancy per woman randomised (studies at low risk of… compared with control (moderate certainty).
2 findings from 1 review
Clinical pregnancy per woman randomised: sensitivity analysis (no high‐risk) · women undergoing assisted reproduction
Endometrial injury showed no clear difference in clinical pregnancy per woman randomised: sensitivity analysis (no… compared with control (low certainty).
1 finding from 1 review
Adverse events due to periodontal therapy · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes adverse events due to periodontal therapy compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
Cardiovascular events · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all cardiovascular events compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
All CVD-related death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all CVD-related death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
All‐cause death · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
It is very uncertain whether scaling and root planing (SRP) plus antibiotics (amoxicillin and… changes all-cause death compared with supragingival scaling (plus placebo) (very low certainty).
1 finding from 1 review
CRP (mg/dL) at end of study · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Fibrinogen · People with periodontitis and metabolic syndrome (no CVD; primary prevention)
1 finding from 1 review
Cost of the intervention · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Acceptability and feasibility of the intervention to patients and dentists · Dental healthcare providers (dentist, dental surgery assistant, dental hygienist, dental technologist, dental laboratory staff, dental…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Failed apnea reduction · treatment of apnea
Doxapram showed no clear difference in 1a. Failed apnea reduction after 2–7 days – doxapram compared to no… compared with no treatment, placebo, methylxanthine (including theophylline,… (low certainty).
3 findings from 1 review
RR 0.45 [0.2, 1.05]
1 study · 21 participants
Low
RR 1.35 [0.53, 3.45]
4 studies · 84 participants
Very low
RR 0.08 [0.01, 1.17]
1 study · 10 participants
Very low