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Evidence found and GRADE certainty

331 questions · 361 findings · 31 reviews

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No studies found 91 · 25.2%GRADE not reported 60 · 16.6%Very low 125 · 34.6%Low 49 · 13.6%Moderate 32 · 8.9%High 4 · 1.1%

Endovenous laser ablation (EVLA) vs foam sclerotherapy

Technical success · people with GSV incompetence

Endovenous laser ablation (EVLA) showed no clear difference in technical success (< 5 years) compared with ultrasound‐guided foam sclerotherapy (UGFS) (low certainty).

2 findings from 1 review

Summary of findings table ‐ Other therapies (cryotherapy) vs other therapies (fractional CO2 laser)

Short‐term hair regrowth ≥ 75% (between 12 and 26 weeks of · adults with alopecia areata

It is very uncertain whether summary of findings table ‐ Other therapies (cryotherapy) changes short‐term hair regrowth ≥ 75% compared with other therapies (fractional CO2 laser) (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Self-reported joint pain when chewing · People with temporomandibular disorders (TMD)

The review found no eligible studies for this question.

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Depression · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in depression compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Severity of joint noise · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes severity of joint noise compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Participant satisfaction or quality of life · People with temporomandibular disorders (TMD)

Occlusal splint led to lower participant satisfaction or quality of life compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Muscle pain when chewing · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes muscle pain when chewing compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Joint pain at rest · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes joint pain at rest compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Frequency of joint noise · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes frequency of joint noise compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Muscle pain at rest · People with temporomandibular disorders (TMD)

It is very uncertain whether occlusal splint changes muscle pain at rest compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Somatisation · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in somatisation compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Occlusal splint vs Physical therapy (ultrasound, exercise, sensorimotor training, laser, TENS, manual therapy)

Range of mandibular motion · People with temporomandibular disorders (TMD)

Occlusal splint showed no clear difference in range of mandibular motion compared with physical therapy (ultrasound, exercise, sensorimotor training,…; GRADE not reported.

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Pain (mean score) · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes pain (mean score) compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review

Clobetasol propionate ointment vs Low-level laser therapy (LLLT)

Clinical score · People with symptomatic, biopsy-confirmed oral lichen planus (OLP); not concurrently receiving other OLP treatment

It is very uncertain whether clobetasol propionate ointment changes clinical score compared with low-level laser therapy (LLLT) (very low certainty).

1 finding from 1 review