Adverse effects: unspecified extrapyramidal symptoms · patients with schizophrenia
Quetiapine probably leads to lower extrapyramidal effects compared with typical antipsychotics (moderate certainty).
1 finding from 1 review
Prolactin level Average level in ng/mL · patients with schizophrenia
1 finding from 1 review
Desired sedation ‐ ultra short term ‐ asleep at 12 hours · patients with schizophrenia
BENZODIAZEPINES showed no clear difference in desired sedation ‐ ultra short term ‐ asleep at 12 hours compared with ANTIPSYCHOTICS (low certainty).
1 finding from 1 review
No clinically important response to treatment ‐ ultra short term (at 12 hours) · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES changes no clinically important response to treatment ‐ ultra short term (at… compared with ANTIPSYCHOTICS (very low certainty).
2 findings from 1 review
No clinically important response to treatment ‐ short term · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES changes no clinically important response to treatment ‐ short term compared with ANTIPSYCHOTICS (very low certainty).
1 finding from 1 review
Unacceptability of treatment (drop-outs / leaving study early) · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES changes leaving the study early due to any reason (overall acceptability of… compared with ANTIPSYCHOTICS (very low certainty).
1 finding from 1 review
Adverse effects (drop‐outs due to adverse effects4) · patients with schizophrenia
It is very uncertain whether BENZODIAZEPINES changes leaving the study early due to adverse effects (overall tolerability… compared with ANTIPSYCHOTICS (very low certainty).
1 finding from 1 review
Behaviour: Leaving the study early (short‐term) · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ any reason compared with typical antipsychotics (low certainty).
1 finding from 1 review
Leaving the study early ‐ short term ‐ due to lack of efficacy · patients with schizophrenia
It is very uncertain whether levomepromazine changes leaving the study early ‐ short term ‐ due to lack of efficacy compared with atypical antipsychotics (very low certainty).
1 finding from 1 review
Leaving the study early ‐ short term ‐ due to patient deterioration · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ due to patient deterioration compared with atypical antipsychotics (moderate certainty).
1 finding from 1 review
Leaving the study early ‐ short term ‐ lost to · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ lost to compared with atypical antipsychotics (low certainty).
1 finding from 1 review
Leaving the study early ‐ short term ‐ due to lack of efficacy · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ due to lack of efficacy compared with typical antipsychotics (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ due to adverse events compared with typical antipsychotics (low certainty).
1 finding from 1 review
Leaving the study early ‐ medium term ‐ any reason · patients with schizophrenia
It is very uncertain whether levomepromazine changes leaving the study early ‐ medium term ‐ any reason compared with typical antipsychotics (very low certainty).
1 finding from 1 review
Acceptability of treatment ‐ leaving the study early · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ long term ‐ any reason compared with typical antipsychotics (moderate certainty).
1 finding from 1 review
Leaving the study early ‐ long term ‐ due to adverse events · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ long term ‐ due to adverse events compared with typical antipsychotics (moderate certainty).
1 finding from 1 review
Leaving the study early ‐ long term ‐ lost to · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ long term ‐ lost to compared with typical antipsychotics (moderate certainty).
1 finding from 1 review
Behaviour: Leaving the study early (short‐term) · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ any reason compared with atypical antipsychotics (low certainty).
1 finding from 1 review
Withdrawals due to adverse events · patients with schizophrenia
Levomepromazine showed no clear difference in leaving the study early ‐ short term ‐ due to adverse events compared with atypical antipsychotics (moderate certainty).
1 finding from 1 review
Relapse · patients with schizophrenia
CLOZAPINE probably leads to lower relapse ‐ short term compared with TYPICAL ANTIPSYCHOTICS ‐ OVERALL (moderate certainty).
4 findings from 1 review
RR 0.62 [0.45, 0.84]
19 studies · 1303 participants
Moderate
RR 0.22 [0.14, 0.34]
4 studies · 578 participants
Moderate
RR 1.04 [0.61, 1.78]
4 studies · 396 participants
Moderate
Show 1 more finding