Findings

What do systematic reviews say?

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Summary of findings: anti‐pseudomonal antibiotics vs placebo

FEV1 % predicted · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 1130 participants
Low

Summary of findings: anti‐pseudomonal antibiotics vs placebo

FVC · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
10 studies · 1097 participants
Low

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Frequency of hospital admissions for pulmonary exacerbations ‐ not measured · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

Summary of findings: anti‐pseudomonal antibiotics may leads to lower pulmonary exacerbations: frequency of one or more hospital admissions compared with placebo (low certainty).

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
RR 0.66 [0.47, 0.93]
3 studies · 946 participants
Low

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Quality of life: lost school or working days · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 245 participants
Low

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Survival: number of deaths · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

Summary of findings: anti‐pseudomonal antibiotics showed no clear difference in survival: number of deaths compared with placebo (low certainty).

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
RR 0.17 [0.03, 1.09]
2 studies · 767 participants
Low

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Antibiotic resistance: frequency of tobramycin‐resistant P aeruginosa · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

Summary of findings: anti‐pseudomonal antibiotics showed no clear difference in antibiotic resistance: frequency of tobramycin‐resistant P aeruginosa compared with placebo (moderate certainty).

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
RR 1.95 [0.86, 4.42]
2 studies · 672 participants
Moderate

Summary of findings: anti‐pseudomonal antibiotics vs placebo

Adverse events · adults and children with cystic fibrosis and a positive microbiological isolate of P aeruginosa from a respiratory tract specimen

1 finding from 1 review

Inhaled anti‐pseudomonal antibiotics for long‐term therapy in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 1014 participants
Very low

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

Mortality (respiratory events) ‐ not reported · acute respiratory distress in hospitalised infants and children

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

Oxygen saturation (SaO2) ‐ not reported · acute respiratory distress in hospitalised infants and children

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

PaO 2 · acute respiratory distress in hospitalised infants and children

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 50 participants
Very low

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

Blood gases (PaCO2) ‐ not reported · acute respiratory distress in hospitalised infants and children

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

Lung function (PaO2/FiO2 ratio) ‐ not reported · acute respiratory distress in hospitalised infants and children

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

Oxygenation index (FiO2% X MPAW/PaO2) ‐ not reported · acute respiratory distress in hospitalised infants and children

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Good‐lung independent vs good‐lung dependent

Episodes of apnoea · acute respiratory distress in hospitalised infants and children

The review found no eligible studies for this question.

1 finding from 1 review

Positioning for acute respiratory distress in hospitalised infants and children 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: unconditional cash transfer vs conditional cash transfers: primary outcomes

Has used any health service in previous 1 to 12 months · children (0 to 17 years) and adults (≥ 18 years) or households

1 finding from 1 review

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health… 2022 · Cochrane Headline outcomes only
no estimate extracted
2559 participants
Very low

Summary of findings: unconditional cash transfer vs conditional cash transfers: primary outcomes

Is moderately stunted · children (0 to 17 years) and adults (≥ 18 years) or households

The review found no eligible studies for this question.

1 finding from 1 review

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: unconditional cash transfer vs conditional cash transfers: primary outcomes

Has died · children (0 to 17 years) and adults (≥ 18 years) or households

The review found no eligible studies for this question.

1 finding from 1 review

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: unconditional cash transfer vs conditional cash transfers: primary outcomes

Has had any illness in previous 2 weeks to 3 months · children (0 to 17 years) and adults (≥ 18 years) or households

It is very uncertain whether summary of findings: unconditional cash transfers changes has had any illness in previous 2 weeks to 3 months compared with conditional cash transfers: primary outcomes (very low certainty).

1 finding from 1 review

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health… 2022 · Cochrane Headline outcomes only
RR 1.11 [0.95, 1.25]
3896 participants
Very low

Summary of findings: unconditional cash transfer vs conditional cash transfers: primary outcomes

Has been food secure · children (0 to 17 years) and adults (≥ 18 years) or households

The review found no eligible studies for this question.

1 finding from 1 review

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health… 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings: unconditional cash transfer vs conditional cash transfers: primary outcomes

Dietary diversity · children (0 to 17 years) and adults (≥ 18 years) or households

1 finding from 1 review

Unconditional cash transfers for reducing poverty and vulnerabilities: effect on use of health services and health… 2022 · Cochrane Headline outcomes only
no estimate extracted
3896 participants
Very low