Death · patients requiring haemodialysis
1 finding from 1 review
Adverse events · patients requiring haemodialysis
It is very uncertain whether summary of findings table ‐ High sodium dialysate changes adverse events compared with standard sodium dialysate (very low certainty).
1 finding from 1 review
Range of mandibular motion · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in range of mandibular motion compared with another occlusal splint with a different mechanism of action; GRADE not reported.
1 finding from 1 review
Participant satisfaction · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
The review found no eligible studies for this question.
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
Goel 2015 (3-arm: intralesional betamethasone vs lycopene vs placebo, 90 per arm): appeared to show increased interincisal distance in both intervention groups vs placebo, but only between-group differences with no…
1 study · 180 participants
GRADE not reported
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional triamcinolone changes burning sensation (VAS 0-100) compared with intralesional triamcinolone plus salvianolic acid B (very low certainty).
2 findings from 1 review
MD -1.00 [-10.37, 8.37]
1 study · 28 participants
Very low
MD -16.30 [-28.15, -4.45]
1 study · 28 participants
Very low
Muscle pain at rest · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Range of mandibular motion · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in range of mandibular motion compared with no treatment or placebo (non-occlusal or transparent-foil placebo…; GRADE not reported.
1 finding from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional steroid injections changes burning sensation (VAS 0-100) compared with alternative medicinal treatments (very low certainty).
2 findings from 1 review
Improvement in range of jaw movement · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
The review found no eligible studies for this question.
1 finding from 1 review
Burning sensation (VAS 0-100) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether intralesional dexamethasone injections changes burning sensation (VAS 0-100) compared with placebo injections (very low certainty).
2 findings from 1 review
MD -52.00 [-62.04, -41.96]
1 study · 25 participants
Very low
MD -46.00 [-53.44, -38.56]
1 study · 25 participants
Very low
Frequency of joint noise · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes frequency of joint noise compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).
1 finding from 1 review
Range of mandibular motion · People with temporomandibular disorders (TMD)
Occlusal splint showed no clear difference in range of mandibular motion compared with behavioural therapy (counselling, CBT, relaxation, self-care…; GRADE not reported.
1 finding from 1 review
Adverse effects · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
1 finding from 1 review
Joint pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes joint pain at rest compared with pharmacological therapy (very low certainty).
1 finding from 1 review
Quality of life · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
The review found no eligible studies for this question.
1 finding from 1 review
Recurrence · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Severity of joint noise · People with temporomandibular disorders (TMD)
The review found no eligible studies for this question.
1 finding from 1 review
Muscle pain at rest · People with temporomandibular disorders (TMD)
It is very uncertain whether occlusal splint changes muscle pain at rest compared with physical therapy (ultrasound, exercise, sensorimotor training,… (very low certainty).
1 finding from 1 review
Maximal mouth opening (interincisal distance) · People of any age with a confirmed diagnosis, by clinical examination and biopsy, of oral submucous fibrosis (OSF)
It is very uncertain whether tongue depressor stretches (physiotherapy) changes maximal mouth opening (interincisal distance) compared with intralesional steroid plus hyaluronidase injections (very low certainty).
1 finding from 1 review