Findings

What do systematic reviews say?

2,532 questions · 2,642 findings · 483 reviews · Headline outcomes only

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No studies found 534 · 20.2%GRADE not reported 82 · 3.1%Very low 641 · 24.3%Low 807 · 30.5%Moderate 472 · 17.9%High 106 · 4%

Intervention not reported

Quality of life (at study completion) EuroQol (VAS) from 0 to 200 mm; higher score means better function · People with hip or knee osteoarthritis

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 214 participants
Very low

Intervention not reported

Adverse effects (related to the exercise programs) · People with hip or knee osteoarthritis

It is very uncertain whether the intervention changes adverse effects (related to the exercise programs) (very low certainty).

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
Peto OR 1.72 [0.51, 5.81]
4 studies · 364 participants
Very low

Intervention not reported

Severe adverse events or withdrawals (due to adverse events) ‐ not reported · People with hip or knee osteoarthritis

The review found no eligible studies for this question.

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Subgroup analysis: Exercise duration vs resistance

Pain ‐ duration exercise WOMAC (VAS or Likert) from 0 to 20 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 200 participants
Very low

Subgroup analysis: Exercise duration vs resistance

Pain ‐ resistance exercise WOMAC (VAS or Likert) from 0 to 20 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 113 participants
Very low

Subgroup analysis: Exercise duration vs resistance

Function ‐ duration exercise WOMAC from 0 to 68 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 200 participants
Very low

Subgroup analysis: Exercise duration vs resistance

Function ‐ resistance exercise WOMAC from 0 to 68 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 113 participants
Low

Intervention not reported

Total mortality Systolic targets · Diabetes Mellitus with elevated blood pressure

The intervention showed no clear difference in total mortality Systolic targets (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in people with diabetes mellitus 2013 · Cochrane Headline outcomes only
RR 1.05 [0.84, 1.3]
1 study · 4734 participants
Low

Intervention not reported

Total mortality Diastolic targets · Diabetes Mellitus with elevated blood pressure

It is very uncertain whether the intervention changes total mortality Diastolic targets (very low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in people with diabetes mellitus 2013 · Cochrane Headline outcomes only
RR 0.73 [0.53, 1.01]
4 studies · 2580 participants
Very low

Intervention not reported

Total serious adverse events Systolic targets · Diabetes Mellitus with elevated blood pressure

The intervention showed no clear difference in total serious adverse events Systolic targets (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in people with diabetes mellitus 2013 · Cochrane Headline outcomes only
RR 1.01 [0.91, 1.13]
1 study · 4734 participants
Low

Intervention not reported

Creatine phosphate 1g/day · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 13 participants
Low

Intervention not reported

Creatine 20g/day for 6 weeks · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 13 participants
Low

Intervention not reported

Creatine 20g/day for 10 days · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Low

Intervention not reported

Creatinine phosphate 1g/day for 6 months · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
Low

Intervention not reported

Creatinine phosphate 1g/day for 3 months · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Intervention not reported

Peak exercise capacity: Power (W) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 367 participants
Moderate

Intervention not reported

Peak exercise capacity: Peak oxygen consumption (VO2peak) (L/min) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 188 participants
Moderate

Intervention not reported

Peak exercise test: Lactate threshold (L/min) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 94 participants
Moderate

Intervention not reported

Peak exercise test: Isowork minute ventilation (VE) (L) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 77 participants
Low

Intervention not reported

Peak exercise test: Isowork dyspnoea score · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low